INT131889

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Context Info
Confidence 0.02
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 1.01

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

pigmentation (gr) plasma membrane (Grin1) enzyme binding (Grin1)
cytoplasm (Grin1)
Anatomy Link Frequency
spinal 2
gr (Mus musculus)
Grin1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Morphine 13 100.00 Very High Very High Very High
tolerance 2 95.24 Very High Very High Very High
Kinase C 1 91.04 High High
nMDA receptor 2 90.00 High High
Spinal cord 2 81.44 Quite High
Dorsal horn 2 80.48 Quite High
intrathecal 3 74.08 Quite High
antagonist 1 69.84 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Here we show that the expression of spinal NMDAR and PKCgamma after chronic morphine is regulated by spinal GR through a cAMP response element-binding protein (CREB)-dependent pathway.
GR Regulation (regulated) of Gene_expression (expression) of NMDAR in spinal associated with morphine
1) Confidence 0.02 Published 2005 Journal J. Neurosci. Section Abstract Doc Link 16319314 Disease Relevance 0 Pain Relevance 1.01

General Comments

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