INT131894

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Context Info
Confidence 0.43
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 3
Disease Relevance 3.26
Pain Relevance 1.61

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transmembrane transport (Kcna6)
Anatomy Link Frequency
brain 4
neurons 2
Kcna6 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
ischemia 27 99.96 Very High Very High Very High
hyperexcitability 9 88.24 High High
Neuronal excitability 9 75.84 Quite High
anesthesia 3 25.00 Low Low
Disease Link Frequency Relevance Heat
Cv Unclassified Under Development 27 99.96 Very High Very High Very High
Hypoxia 9 99.54 Very High Very High Very High
Stroke 6 78.28 Quite High
Convulsion 3 75.76 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Hypoxia/ischemia in rat brain induced a dramatic dephosphorylation of Kv2.1 and the translocation of surface Kv2.1 from clusters to a uniform localization.
Positive_regulation (induced) of Phosphorylation (dephosphorylation) of Kv2 in brain associated with hypoxia and ischemia
1) Confidence 0.43 Published 2005 Journal J. Neurosci. Section Abstract Doc Link 16319318 Disease Relevance 1.09 Pain Relevance 0.52
In cultured rat hippocampal neurons, chemical ischemia (CI) elicited a similar dephosphorylation and translocation of Kv2.1.
Positive_regulation (elicited) of Phosphorylation (dephosphorylation) of Kv2 in neurons associated with ischemia
2) Confidence 0.40 Published 2005 Journal J. Neurosci. Section Abstract Doc Link 16319318 Disease Relevance 1.08 Pain Relevance 0.56
Hypoxia/ischemia in rat brain induced a dramatic dephosphorylation of Kv2.1 and the translocation of surface Kv2.1 from clusters to a uniform localization.
Positive_regulation (induced) of Phosphorylation (dephosphorylation) of Kv2 in brain associated with hypoxia and ischemia
3) Confidence 0.35 Published 2005 Journal J. Neurosci. Section Abstract Doc Link 16319318 Disease Relevance 1.10 Pain Relevance 0.53

General Comments

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