INT131967

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Context Info
Confidence 0.67
First Reported 2006
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.73
Pain Relevance 0.82

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Grik2) plasma membrane (Grik2)
Grik2 (Mus musculus)
Pain Link Frequency Relevance Heat
Glutamate receptor 5 100.00 Very High Very High Very High
Serotonin 14 99.56 Very High Very High Very High
Enkephalin 2 98.28 Very High Very High Very High
cocaine 7 97.44 Very High Very High Very High
dopamine receptor 2 86.88 High High
Dynorphin 1 85.96 High High
substance P 1 85.52 High High
Neuropeptide 2 85.00 Quite High
addiction 1 68.40 Quite High
adenocard 11 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 13 96.76 Very High Very High Very High
Epilepsy 9 76.28 Quite High
Neurodegenerative Disease 2 55.52 Quite High
Cocaine Dependence 1 49.56 Quite Low
Motor Neuron Diseases 14 5.00 Very Low Very Low Very Low
Cancer 9 5.00 Very Low Very Low Very Low
Schizophrenia 5 5.00 Very Low Very Low Very Low
Death 5 5.00 Very Low Very Low Very Low
Glioblastoma 5 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast, mutant mice showed altered response in mRNA levels of N-methyl-D-aspartate, GLUR5 and GLUR6 glutamate receptor subunits as well as of enkephalin following cocaine administration.
Transcription (levels) of GLUR6 associated with glutamate receptor, enkephalin and cocaine
1) Confidence 0.67 Published 2006 Journal Neuroscience Section Abstract Doc Link 16326019 Disease Relevance 0.39 Pain Relevance 0.72
These would include mRNA transcripts of the AMPA and kainate members of the glutamate receptor family – GluR-B, GluR-5 & GluR-6 [33], the serotonin 5-HT2C receptor [45], the ?
Transcription (transcripts) of GluR-6 associated with glutamate receptor and serotonin
2) Confidence 0.06 Published 2009 Journal Mol Brain Section Body Doc Link PMC2694175 Disease Relevance 0.33 Pain Relevance 0.10

General Comments

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