INT132060

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.01
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 3
Disease Relevance 0.21
Pain Relevance 0.49

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

intracellular (NBN, Nos2) nucleus (NBN, Nos2) nucleoplasm (NBN)
aging (Nos2) peroxisome (Nos2) cytoplasm (Nos2)
NBN (Homo sapiens)
Nos2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
ischemia 3 82.88 Quite High
isoflurane 3 79.40 Quite High
ketamine 3 77.64 Quite High
anesthesia 3 76.60 Quite High
COX2 3 25.00 Low Low
Disease Link Frequency Relevance Heat
Coronary Artery Disease 3 82.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We conclude that ATV reduced IS by increasing the activity of iNOS and COX-2, iNOS is upstream to COX-2, and iNOS activates COX-2 by S-nitrosylation.
ATV Positive_regulation (increasing) of iNOS
1) Confidence 0.01 Published 2006 Journal Am. J. Physiol. Heart Circ. Physiol. Section Abstract Doc Link 16339820 Disease Relevance 0.06 Pain Relevance 0.14
ATV increased calcium-independent NOS (iNOS) [11.9 (SD 0.8) vs. 3.9 (SD 0.1) x 1,000 counts/min; P < 0.001] and COX-2 [46.7 (SD 1.1) vs. 6.5 (SD 1.4) pg/ml of 6-keto-PGF(1alpha); P < 0.001] activity.
ATV Positive_regulation (increased) of iNOS
2) Confidence 0.01 Published 2006 Journal Am. J. Physiol. Heart Circ. Physiol. Section Abstract Doc Link 16339820 Disease Relevance 0.08 Pain Relevance 0.20
We conclude that ATV reduced IS by increasing the activity of iNOS and COX-2, iNOS is upstream to COX-2, and iNOS activates COX-2 by S-nitrosylation.
ATV Positive_regulation (increasing) of iNOS
3) Confidence 0.01 Published 2006 Journal Am. J. Physiol. Heart Circ. Physiol. Section Abstract Doc Link 16339820 Disease Relevance 0.06 Pain Relevance 0.14

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox