INT132241

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Context Info
Confidence 0.49
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.70
Pain Relevance 0.59

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Nfkb1) DNA binding (Nfkb1) protein complex (Nfkb1)
cytoplasm (Nfkb1) cytosol (Nfkb1) signal transduction (Nfkb1)
Anatomy Link Frequency
spinal cord dorsal horn 2
Nfkb1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Spinal cord 4 99.00 Very High Very High Very High
Dorsal horn 4 98.52 Very High Very High Very High
antagonist 1 93.68 High High
Glutamate 4 78.88 Quite High
Peripheral nerve injury 2 69.28 Quite High
Inflammation 1 67.36 Quite High
Neuropathic pain 1 42.80 Quite Low
Disease Link Frequency Relevance Heat
Nervous System Injury 8 99.98 Very High Very High Very High
INFLAMMATION 1 67.36 Quite High
Injury 1 65.44 Quite High
Neuropathic Pain 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, CCI induced a significant downregulation of nuclear factor kappaB (NF-kappaB) within the ipsilateral spinal cord dorsal horn, which also was attenuated by either RU38486 (4 > 2 = 0.5 microg = vehicle) or a GR antisense oligonucleotide.
Positive_regulation (induced) of Negative_regulation (downregulation) of NF-kappaB in spinal cord dorsal horn associated with nervous system injury, dorsal horn and spinal cord
1) Confidence 0.49 Published 2006 Journal Pain Section Abstract Doc Link 16360273 Disease Relevance 0.70 Pain Relevance 0.59

General Comments

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