INT132384

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.20
First Reported 2006
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 6
Disease Relevance 1.27
Pain Relevance 0.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

RNA binding (Msi1) nucleus (Msi1) cytoplasm (Msi1)
Anatomy Link Frequency
stem cells 2
excretory duct cells 1
Salivary gland 1
Msi1 (Mus musculus)
Pain Link Frequency Relevance Heat
Substantia nigra 1 83.20 Quite High
midbrain 1 77.76 Quite High
GABAergic 1 73.52 Quite High
Hippocampus 1 72.08 Quite High
tetrodotoxin 1 63.28 Quite High
sodium channel 1 61.44 Quite High
Action potential 1 60.08 Quite High
gABA 1 56.08 Quite High
Glutamate 1 53.52 Quite High
anesthesia 10 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Salivary Gland Disease 60 91.08 High High
Disease 7 90.16 High High
Syndrome 10 87.80 High High
Xerostomia 30 87.44 High High
Cancer 15 78.40 Quite High
Malignant Neoplastic Disease 10 76.88 Quite High
Neurodegenerative Disease 2 75.76 Quite High
Head & Neck Cancer 15 75.44 Quite High
Targeted Disruption 20 73.56 Quite High
Reprotox - General 1 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Salivary gland cells were isolated from murine submandibular glands and cultured in vitro as salispheres, which contained cells expressing the stem cell markers Sca-1, c-Kit and Musashi-1.
Gene_expression (expressing) of Musashi-1 in Salivary gland
1) Confidence 0.20 Published 2008 Journal PLoS ONE Section Abstract Doc Link PMC2329592 Disease Relevance 0.49 Pain Relevance 0
The onset of differentiation after 5 days of culture and the gradual loss of Sca-1, c-Kit and Musashi-1 expression after 3 days of culture indicated that for subsequent functional experiments employing transplantation, cells that had been cultured for 3 days were most suitable.


Gene_expression (expression) of Musashi-1
2) Confidence 0.20 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2329592 Disease Relevance 0 Pain Relevance 0
Concomitantly, the percentage of cells expressing common stem cell markers Sca-1, c-Kit and Musashi-1 decreased in time.
Gene_expression (expressing) of Musashi-1 in stem cell
3) Confidence 0.15 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2329592 Disease Relevance 0.40 Pain Relevance 0
Finally, Musashi-1 was expressed almost exclusively in the nuclei of excretory duct cells and very rarely in striated duct cells (Fig. 4D).
Gene_expression (expressed) of Musashi-1 in excretory duct cells
4) Confidence 0.15 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2329592 Disease Relevance 0.15 Pain Relevance 0
It has been shown that putative stem cells from multiple organs express Sca-1 [19], [26], [31], [32], c-Kit [30] and Musashi-1 [27].
Gene_expression (express) of Musashi-1 in stem cells
5) Confidence 0.15 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2329592 Disease Relevance 0 Pain Relevance 0
These tNSCs showed neurosphere formation and expressed high levels of early neuroectodermal markers, such as the proneural genes NeuroD1, Neurog2, and Olig2, the NSC markers Nestin and Musashi1, and the proliferation markers Ki67 and BrdU (5-bromo-2-deoxyuridine).
Gene_expression (expressed) of Musashi1
6) Confidence 0.07 Published 2006 Journal Stem Cells Section Abstract Doc Link 16373695 Disease Relevance 0.23 Pain Relevance 0.33

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox