INT132459

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Context Info
Confidence 0.35
First Reported 2005
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 2.19
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (FABP3) cytoskeletal protein binding (FABP3) cytosol (FABP3)
Anatomy Link Frequency
blood 2
plasma 1
chest 1
FABP3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 3 97.56 Very High Very High Very High
Inflammation 21 86.96 High High
ischemia 26 62.80 Quite High
addiction 1 60.40 Quite High
Angina 42 49.96 Quite Low
imagery 27 47.96 Quite Low
metalloproteinase 5 23.64 Low Low
antagonist 3 5.00 Very Low Very Low Very Low
Calcium channel 2 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Albuminuria 4 99.08 Very High Very High Very High
Pain 3 97.56 Very High Very High Very High
Heart Rate Under Development 8 96.32 Very High Very High Very High
Acute Coronary Syndrome 73 95.12 Very High Very High Very High
Infarction 5 93.52 High High
Autosomal Dominant Polycystic Kidney 111 93.20 High High
Natriuresis 18 91.60 High High
Myocardial Infarction 86 90.88 High High
INFLAMMATION 23 86.96 High High
Emergencies 10 84.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
More recently a semi quantitative test CardioDetect using the early release of h-FABP (heart fatty acid binding) showed a better sensibility in the first hours after chest-pain onset in out-door patients.
h-FABP Binding (binding) of in chest associated with pain
1) Confidence 0.35 Published 2005 Journal Arch Mal Coeur Vaiss Section Abstract Doc Link 16379107 Disease Relevance 0.84 Pain Relevance 0.10
After placing three drops of whole blood onto a test strip of CardioDetect® med, H-FABP in the serum was bound to the monoclonal antibody resulting in a red line within 15 min.
H-FABP Binding (bound) of in blood
2) Confidence 0.15 Published 2011 Journal Journal of Korean Medical Science Section Body Doc Link PMC3012849 Disease Relevance 0.15 Pain Relevance 0
Because H-FABP has predominantly a renal clearance and renal function decreases with age, plasma H-FABP may increase with age (Tsuji R et al. 1993).
H-FABP Binding (increase) of in plasma
3) Confidence 0.06 Published 2008 Journal Biomarker Insights Section Body Doc Link PMC2688349 Disease Relevance 0.39 Pain Relevance 0.03
In addition, B2M and H-FABP were associated inversely with measured GFR and effective renal blood flow independent of albuminuria; KIM-1, NGAL, and MCP-1 were associated positively with total renal volume independent of albuminuria [54].
H-FABP Binding (associated) of in blood associated with albuminuria
4) Confidence 0.04 Published 2011 Journal International Journal of Nephrology Section Body Doc Link PMC3017903 Disease Relevance 0.81 Pain Relevance 0.07

General Comments

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