INT132477

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Context Info
Confidence 0.45
First Reported 2005
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 3.24
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (TSHB) extracellular region (TSHB) cellular nitrogen compound metabolic process (TSHB)
cell-cell signaling (TSHB)
Anatomy Link Frequency
thyroid 4
TSHB (Homo sapiens)
Pain Link Frequency Relevance Heat
depression 24 90.92 High High
biopsychosocial 7 50.00 Quite Low
withdrawal 7 5.00 Very Low Very Low Very Low
beta blocker 4 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Analgesic 2 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
tolerance 2 5.00 Very Low Very Low Very Low
iatrogenic 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypothyroidism 35 99.10 Very High Very High Very High
Cancer 15 99.04 Very High Very High Very High
Thyroid Neoplasm 95 98.46 Very High Very High Very High
Disease 36 94.12 High High
Constipation 1 94.12 High High
Heart Rate Under Development 2 93.56 High High
Hoarseness 1 92.64 High High
Weight Gain 14 92.16 High High
Thyroiditis 2 91.60 High High
Depression 26 90.92 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Serum hormonal assay indicated a decrease in testosterone and follicular stimulating hormone levels in treated rats.
Negative_regulation (decrease) of stimulating hormone
1) Confidence 0.45 Published 2005 Journal Neuro Endocrinol. Lett. Section Body Doc Link 16380694 Disease Relevance 0 Pain Relevance 0
The reasons for impaired quality of life in thyroid cancer survivors in whom the cancer has been cured are not well-understood are not related to thyroid stimulating hormone (TSH) levels [27].
Neg (not) Negative_regulation (related) of thyroid stimulating hormone in thyroid associated with thyroid neoplasm and cancer
2) Confidence 0.30 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2615133 Disease Relevance 1.25 Pain Relevance 0
In particular, six consecutive nights of sleep restriction (four hours sleep per night) were associated with increases in sympathetic nervous system (SNS) activity, evening cortisol levels and growth hormone levels (GH), and reductions in thyroid stimulating hormone (TSH), and leptin [16, 17, 41].
Negative_regulation (reductions) of thyroid stimulating hormone in thyroid
3) Confidence 0.13 Published 2010 Journal Journal of Obesity Section Body Doc Link PMC2925323 Disease Relevance 0.27 Pain Relevance 0
Serum levels of thyroid stimulating hormone (TSH) and total thyroxine (T4) were only available for 2,299 participants ?
Negative_regulation (levels) of thyroid stimulating hormone in thyroid
4) Confidence 0.08 Published 2006 Journal Environ Health Perspect Section Body Doc Link PMC1764147 Disease Relevance 0 Pain Relevance 0
Laboratory testing in individuals with primary overt hypothyroidism typically depicts an elevated serum thyroid stimulating hormone (TSH) level, and a decrease in serum free-thyroxine (FT4) levels [3].
Negative_regulation (decrease) of stimulating hormone in thyroid associated with hypothyroidism
5) Confidence 0.06 Published 2010 Journal Trials Section Body Doc Link PMC2992059 Disease Relevance 1.71 Pain Relevance 0.05

General Comments

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