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Context Info
Confidence 0.16
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.32
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (RASGRP1, OPCML) cell differentiation (RASGRP1) Golgi apparatus (RASGRP1)
endoplasmic reticulum (RASGRP1) cytoplasm (RASGRP1) cytosol (RASGRP1)
Anatomy Link Frequency
T29H 1
RASGRP1 (Homo sapiens)
OPCML (Homo sapiens)
Pain Link Frequency Relevance Heat
Opioid 1 55.04 Quite High
Disease Link Frequency Relevance Heat
Ovarian Cancer 4 74.92 Quite High
Cancer 1 58.48 Quite High
Adhesions 1 56.24 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, suppression of oncogenic RAS activity by stable siRNA specific for HRAS(V12) led to the demethylation and re-expression of OPCML in T29H cells, demonstrating that oncogenic RAS activity is directly responsible for the observed OPCML promoter hypermethylation and epigenetic gene silencing of OPCML.
oncogenic RAS Regulation (responsible) of OPCML in T29H
1) Confidence 0.16 Published 2006 Journal FASEB J. Section Abstract Doc Link 16384911 Disease Relevance 0.32 Pain Relevance 0.06

General Comments

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