INT132580

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Context Info
Confidence 0.41
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.27
Pain Relevance 0.45

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (ADRA2C, Htr1a) signal transducer activity (ADRA2C, Htr1a) endosome (ADRA2C)
small molecule metabolic process (ADRA2C) cell-cell signaling (ADRA2C) cytoplasm (ADRA2C)
ADRA2C (Homo sapiens)
Htr1a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antagonist 4 100.00 Very High Very High Very High
Central nervous system 2 92.24 High High
anesthesia 3 68.00 Quite High
agonist 2 64.64 Quite High
Pain 3 38.16 Quite Low
Disease Link Frequency Relevance Heat
Akathisia 1 75.44 Quite High
Pressure And Volume Under Development 1 73.28 Quite High
Sleep Disorders 2 68.72 Quite High
Nociception 1 40.96 Quite Low
Pain 2 38.16 Quite Low
Cognitive Disorder 2 30.08 Quite Low
Parkinson's Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Unlike many other alpha2-adrenoceptor antagonists, it has negligible affinity for 5-HT1A and I2 binding sites.
alpha2-adrenoceptor Binding (affinity) of 5-HT1A associated with antagonist
1) Confidence 0.41 Published 2005 Journal CNS Drug Rev Section Abstract Doc Link 16389294 Disease Relevance 0.27 Pain Relevance 0.45

General Comments

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