INT132617

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Context Info
Confidence 0.42
First Reported 2006
Last Reported 2010
Negated 2
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 1.55
Pain Relevance 0.96

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Gsr) mitochondrion (Gsr) oxidoreductase activity (Gsr)
cytoplasm (Gsr)
Anatomy Link Frequency
paw 1
Gsr (Mus musculus)
Pain Link Frequency Relevance Heat
Paracetamol 8 98.98 Very High Very High Very High
Inflammation 7 96.20 Very High Very High Very High
Analgesic 5 88.44 High High
Disease Link Frequency Relevance Heat
Pressure And Volume Under Development 6 98.76 Very High Very High Very High
INFLAMMATION 7 96.20 Very High Very High Very High
Hepatotoxicity 5 86.24 High High
Drug Induced Neurotoxicity 3 84.24 Quite High
Stress 2 81.92 Quite High
Death 1 70.64 Quite High
Body Weight 1 68.88 Quite High
Injury 1 60.96 Quite High
Gonorrhea 1 49.48 Quite Low
Mycobacterial Infection 1 48.88 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Conversely, MeHg exposure increased cerebellar glutathione reductase activity (mean percentage inhibition of 70%), and this phenomenon was not affected by C. paludosa co-administration.
Neg (not) Regulation (affected) of glutathione reductase
1) Confidence 0.42 Published 2007 Journal Basic Clin. Pharmacol. Toxicol. Section Abstract Doc Link 17651315 Disease Relevance 0.29 Pain Relevance 0
Neither paracetamol treatment alone nor pretreatment with W. paludosa altered glutathione reductase and glutathione S-transferase activity or the levels of end-products of lipid peroxidation.
Neg (nor) Regulation (altered) of glutathione reductase associated with paracetamol
2) Confidence 0.40 Published 2006 Journal J. Pharm. Pharmacol. Section Abstract Doc Link 16393474 Disease Relevance 0.60 Pain Relevance 0.63
We also detected the changes in the activities of superoxide dismutase (SOD), glutathione reductase (GRx) and glutathione peroxidase (GPx) of liver in the lambda-carrageenan-induced paw edema in mice to investigate the anti-inflammatory mechanism of FL and FM.
Regulation (changes) of glutathione reductase in paw associated with pressure and volume under development and inflammation
3) Confidence 0.20 Published 2010 Journal Am. J. Chin. Med. Section Abstract Doc Link 20503477 Disease Relevance 0.66 Pain Relevance 0.34

General Comments

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