INT13272

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Context Info
Confidence 0.44
First Reported 1980
Last Reported 1995
Negated 2
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 0.35
Pain Relevance 3.02

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Gh1) signal transduction (Gh1) mitochondrion (Gh1)
extracellular space (Gh1) extracellular region (Gh1) plasma membrane (Gh1)
Anatomy Link Frequency
plasma 2
Dorsal 2
pituitary 2
Gh1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Morphine 10 100.00 Very High Very High Very High
Somatostatin 8 100.00 Very High Very High Very High
Clonidine 3 100.00 Very High Very High Very High
narcan 2 100.00 Very High Very High Very High
Catecholamine 1 97.00 Very High Very High Very High
Opioid 6 94.92 High High
Serotonin 2 90.64 High High
agonist 3 90.40 High High
opiate 2 90.24 High High
Dopamine 5 90.04 High High
Disease Link Frequency Relevance Heat
Hypoglycemia 2 99.74 Very High Very High Very High
Body Weight 1 84.92 Quite High
Decapitation 1 78.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The inhibition of catecholamine synthesis by alpha-methyl-p-tyrosine blocked the secretory episode of GH following administration of GHB and after insulin hypoglycaemia whereas the GH rise induced by clonidine was unchanged.
Neg (unchanged) Regulation (unchanged) of Positive_regulation (induced) of GH associated with hypoglycemia, catecholamine and clonidine
1) Confidence 0.44 Published 1980 Journal J. Endocrinol. Section Abstract Doc Link 7430898 Disease Relevance 0.19 Pain Relevance 0.56
Dorsal hippocampal implants were without any effect on the morphine-induced GH, PRL or B secretion.
Neg (without) Regulation (effect) of Positive_regulation (morphine-induced) of GH in Dorsal associated with morphine
2) Confidence 0.28 Published 1991 Journal Brain Res. Section Abstract Doc Link 1664769 Disease Relevance 0.08 Pain Relevance 1.26
The involvement of somatostatin (SRIF), GRF and IGFs in mediating GH feedback was evaluated in hypothalamic-pituitary coperifusion.
Regulation (involvement) of Positive_regulation (mediating) of GH in pituitary associated with somatostatin
3) Confidence 0.23 Published 1995 Journal Neuroendocrinology Section Abstract Doc Link 7617136 Disease Relevance 0.08 Pain Relevance 0.30
Contradictory results (12,25) have been obtained concerning the effect of naloxone on basal or stimulated GH and PRL secretion in rats, monkeys and humans when tested by the continuous blood sampling method, which rules out the erroneous evaluation of results caused by episodicity of plasma hormone levels.
Regulation (effect) of Positive_regulation (stimulated) of GH in plasma associated with narcan
4) Confidence 0.14 Published 1981 Journal Adv. Biochem. Psychopharmacol. Section Abstract Doc Link 7010947 Disease Relevance 0 Pain Relevance 0.91

General Comments

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