INT132739

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Context Info
Confidence 0.65
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 1.03
Pain Relevance 3.01

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Plcb1) signal transduction (Plcb1) cell adhesion (Plcb1)
mRNA processing (Plcb1) nucleus (Plcb1) enzyme binding (Plcb1)
Plcb1 (Mus musculus)
Pain Link Frequency Relevance Heat
Pain 6 99.84 Very High Very High Very High
Morphine 14 99.16 Very High Very High Very High
antinociception 4 98.80 Very High Very High Very High
Analgesic 8 98.00 Very High Very High Very High
tolerance 10 97.60 Very High Very High Very High
Opioid 10 97.08 Very High Very High Very High
opioid receptor 4 25.00 Low Low
Disease Link Frequency Relevance Heat
Targeted Disruption 2 100.00 Very High Very High Very High
Pain 6 99.84 Very High Very High Very High
Nociception 8 91.12 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the present study, PLCbeta1 knockout animals (-/-) were used to assess the relevance of PLCbeta1 to pain thresholds, morphine antinociception and analgesic tolerance formation.
Localization (relevance) of PLCbeta1 associated with targeted disruption, antinociception, pain, analgesic, tolerance and morphine
1) Confidence 0.65 Published 2006 Journal Brain Res. Section Abstract Doc Link 16405873 Disease Relevance 0.52 Pain Relevance 1.50
In the present study, PLCbeta1 knockout animals (-/-) were used to assess the relevance of PLCbeta1 to pain thresholds, morphine antinociception and analgesic tolerance formation.
Localization (relevance) of PLCbeta1 associated with targeted disruption, antinociception, pain, analgesic, tolerance and morphine
2) Confidence 0.57 Published 2006 Journal Brain Res. Section Abstract Doc Link 16405873 Disease Relevance 0.51 Pain Relevance 1.51

General Comments

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