INT132754

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Context Info
Confidence 0.39
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.80
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Wrn) intracellular (Wrn) helicase activity (Wrn)
DNA binding (Wrn) nuclease activity (Wrn) nucleolus (Wrn)
Wrn (Mus musculus)
Pain Link Frequency Relevance Heat
ischemia 1 69.52 Quite High
Restless leg syndrome 1 68.72 Quite High
Disease Link Frequency Relevance Heat
Cognitive Disorder 2 97.88 Very High Very High Very High
Aging 2 96.68 Very High Very High Very High
Cancer 1 95.00 High High
Premature Aging 1 93.20 High High
Werner Syndrome 1 91.68 High High
Myocardial Infarction 1 72.24 Quite High
Coronary Artery Disease 1 70.40 Quite High
Increased Venous Pressure Under Development 1 68.72 Quite High
Stroke 1 64.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To test this hypothesis, we assessed the impact of the i1-C/T, L1074F and C1367R polymorphisms in the WRN gene on the occurrence of cardiovascular pathologies, on cognitive performance and on the risks of all-cause, cardiovascular and cancer mortalities in the population-based Leiden 85-plus Study.
Regulation (impact) of WRN gene associated with cognitive disorder and cancer
1) Confidence 0.39 Published 2006 Journal Mech. Ageing Dev. Section Abstract Doc Link 16405962 Disease Relevance 0.80 Pain Relevance 0.10

General Comments

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