INT132809

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Context Info
Confidence 0.33
First Reported 2002
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.26
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (TNF, IL1B) signal transduction (TNF, IL1B) extracellular region (TNF, IL1B)
aging (IL1B) intracellular (TNF) extracellular matrix organization (TNF)
TNF (Homo sapiens)
IL1B (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory mediators 1 95.28 Very High Very High Very High
interstitial cystitis 1 83.84 Quite High
Inflammation 19 54.56 Quite High
metalloproteinase 6 44.88 Quite Low
cytokine 11 39.96 Quite Low
chemokine 11 34.00 Quite Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
rheumatoid arthritis 3 5.00 Very Low Very Low Very Low
COX2 2 5.00 Very Low Very Low Very Low
Freund adjuvant 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 6 100.00 Very High Very High Very High
Necrosis 5 100.00 Very High Very High Very High
INFLAMMATION 21 95.28 Very High Very High Very High
Overactive Bladder 2 86.76 High High
Adhesions 2 86.24 High High
Interstitial Cystitis 1 83.84 Quite High
Death 6 82.32 Quite High
Disease 8 20.68 Low Low
Arthritis 5 5.00 Very Low Very Low Very Low
Apoptosis 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We investigated whether HDSMCs are capable of expressing and releasing MCP-1, IL-6 and SCF in response to IL-4, IL-13, IL-1beta and tumor necrosis factor-alpha.
tumor necrosis factor-alpha Positive_regulation (response) of IL-1beta associated with necrosis and cancer
1) Confidence 0.33 Published 2006 Journal J. Urol. Section Abstract Doc Link 16407046 Disease Relevance 0.60 Pain Relevance 0.08
and TNF (with the exception for RANTES and IP-10), even though it potentiates the proinflammatory activities of TNF or IL-1?.
TNF Positive_regulation (potentiates) of IL-1
2) Confidence 0.13 Published 2002 Journal Arthritis Res Section Body Doc Link PMC83846 Disease Relevance 0.66 Pain Relevance 0.07

General Comments

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