INT13282

Context Info Confidence 0.66 First Reported 1991 Last Reported 1996 Negated 0 Speculated 1 Reported most in Abstract Documents 1 Total Number 2 Disease Relevance 0.21 Pain Relevance 0.91

extracellular space (Fgf2, Ngf) signal transduction (Fgf2, Ngf) extracellular region (Fgf2, Ngf) aging (Ngf) embryo development (Fgf2) cytoplasm (Fgf2)

Anatomy Link Frequency nerve 1 fibroblast 1 Fgf2 (Rattus norvegicus) Ngf (Rattus norvegicus)

Pain Link Frequency Relevance Heat Nerve growth factor 11 100.00 long-term potentiation 8 99.80 Neuropeptide 5 98.72 substance P 5 97.72 Pain 2 86.88 Sciatic nerve 2 75.28 anesthesia 1 25.00

Disease Link Frequency Relevance Heat Pain 2 86.88 Anaerobic Bacterial Infections 2 64.08 Injury 1 26.00 Nervous System Injury 1 5.00

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Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The effects of epidermal growth factor (EGF), basic fibroblast growth factor (bFGF) and nerve growth factor (NGF) on long-term potentiation (LTP) of evoked potential were investigated in the dentate gyrus of anaesthetised rats.

basic fibroblast growth factor Spec (investigated) Regulation (effects) of NGF in fibroblast associated with nerve growth factor and long-term potentiation

1) Confidence 0.66 Published 1991 Journal Neurosci. Res. Section Abstract Doc Link 1664922 Disease Relevance 0.12 Pain Relevance 0.42

Using immunohistochemistry and in situ hybridization the in vivo effects of acidic and basic fibroblast growth factor (aFGF, bFGF), and of nerve growth factor (NGF) on the expression of galanin, neuropeptide Y (NPY) and substance P in axotomized dorsal root ganglia (DRGs) were examined.

basic fibroblast growth factor Regulation (effects) of NGF in nerve associated with nerve growth factor, neuropeptide and substance p

2) Confidence 0.42 Published 1996 Journal Regul. Pept. Section Abstract Doc Link 8916273 Disease Relevance 0.09 Pain Relevance 0.49

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