INT132882

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Context Info
Confidence 0.17
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 1.35
Pain Relevance 1.60

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Slc40a1) plasma membrane (Slc40a1)
Anatomy Link Frequency
lymph nodes 1
lungs 1
Slc40a1 (Mus musculus)
Pain Link Frequency Relevance Heat
Morphine 3 98.92 Very High Very High Very High
agonist 3 98.76 Very High Very High Very High
fibrosis 7 98.40 Very High Very High Very High
Pain 7 96.72 Very High Very High Very High
Endocannabinoid 5 96.44 Very High Very High Very High
narcan 2 93.48 High High
Acute pain 2 85.60 High High
MU agonist 1 83.60 Quite High
Enkephalin 1 81.24 Quite High
Brush evoked pain 1 76.72 Quite High
Disease Link Frequency Relevance Heat
Paracoccidioidomycosis 25 100.00 Very High Very High Very High
Targeted Disruption 2 99.12 Very High Very High Very High
Fibrosis 6 98.40 Very High Very High Very High
Pain 7 96.72 Very High Very High Very High
Injury 1 87.36 High High
Nociception 2 79.36 Quite High
Neuropathic Pain 1 76.72 Quite High
INFLAMMATION 10 72.44 Quite High
Infection 63 71.28 Quite High
Congenital Anomalies 2 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Pulmonary function analysis would respond to the following question: Do the large masses or the consolidated lesions observed in our study by HRCT or the fibrosis recorded by histopathology, decrease the normal function of lungs of mice with experimental PCM?
Gene_expression (experimental) of PCM in lungs associated with paracoccidioidomycosis and fibrosis
1) Confidence 0.17 Published 2010 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2894136 Disease Relevance 0.47 Pain Relevance 0.09
After 2 washes in PBS, DCs were cultured with CD8+ T cells purified from lymph nodes of GagL-TCR-TG transgenic mice [34] (60% of CD8+ cells, of which 98% expressed the GagL-specific TCR, and labeled in the presence of 5 ┬ÁM CFSE).
Gene_expression (expressed) of GagL-specific in lymph nodes associated with targeted disruption
2) Confidence 0.09 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2883599 Disease Relevance 0.17 Pain Relevance 0
DAMGO and DAMGA were full agonist prototypes, morphine, endomorphin-1, endomorphin-1-ol, Dmt-endomorphin-1, endomorphin-2-ol and (D-Met2)-endomorphin-2 were found by both methods to be partial agonists whereas the parameters for normorphine, morphiceptin and endomorphin-2 were intermediate.
Gene_expression (found) of endomorphin-2-ol associated with agonist and morphine
3) Confidence 0.04 Published 2006 Journal Peptides Section Abstract Doc Link 16413634 Disease Relevance 0 Pain Relevance 0.56
Recently, the alpha-ketoheterocycle OL135 has been synthesized and shown to be a highly potent and selective inhibitor of FAAH with efficacy in pain models in vivo.
Gene_expression (synthesized) of OL135 associated with pain
4) Confidence 0.01 Published 2008 Journal Neuroscience Section Abstract Doc Link 18541380 Disease Relevance 0.71 Pain Relevance 0.95

General Comments

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