INT132885

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Context Info
Confidence 0.44
First Reported 2006
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 3.92
Pain Relevance 0.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein complex (SYP)
Anatomy Link Frequency
neuron 2
neural 1
SYP (Homo sapiens)
Pain Link Frequency Relevance Heat
Neuropeptide 2 98.56 Very High Very High Very High
cva 3 75.84 Quite High
backache 1 75.08 Quite High
Enkephalin 3 73.84 Quite High
Somatostatin 9 72.80 Quite High
imagery 18 70.00 Quite High
headache 3 67.44 Quite High
abdominal pain 6 36.56 Quite Low
medulla 2 33.52 Quite Low
Catecholamine 9 21.24 Low Low
Disease Link Frequency Relevance Heat
Adhesions 1 98.78 Very High Very High Very High
Cancer 70 95.12 Very High Very High Very High
Necrosis 13 94.96 High High
Anaplasia 1 94.16 High High
Malignant Neoplastic Disease 13 93.84 High High
Paraganglioma 40 91.68 High High
Disease 5 79.96 Quite High
Recurrence 3 79.52 Quite High
Multiple Endocrine Neoplasia Type 2a 2 76.88 Quite High
Pressure And Volume Under Development 1 75.96 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These cells are immunopositive for neuroendocrine markers including synaptophysin and chromogranin A and for several neuropeptides.
Regulation (immunopositive) of synaptophysin associated with neuropeptide
1) Confidence 0.44 Published 2007 Journal World J Surg Oncol Section Body Doc Link PMC1976114 Disease Relevance 1.14 Pain Relevance 0.20
Immunohistochemistry showed positivity for synaptophysin, neuron specific enolase, chromogranin and cytokeratin.
Regulation (positivity) of synaptophysin in neuron
2) Confidence 0.44 Published 2007 Journal World J Surg Oncol Section Body Doc Link PMC2092435 Disease Relevance 1.10 Pain Relevance 0.08
Both cellular components expressed non-polysialylated neural cell adhesion molecule (NCAM)-L species, and several overlapping areas of synaptophysin and GFAP immunoreactivity were present.
Regulation (immunoreactivity) of synaptophysin in neural associated with adhesions
3) Confidence 0.26 Published 2006 Journal Pathol. Res. Pract. Section Abstract Doc Link 16413693 Disease Relevance 1.20 Pain Relevance 0.10
Formalin-fixed and paraffin-embedded pancreatic tissue was used as a positive control for synaptophysin, chromogranin, and neuron-specific enolase (NSE); hepatic tissue for alpha-fetoprotein (AFP) and Hep-Par1; and epidermis for cytokeratin.
Regulation (control) of synaptophysin in neuron
4) Confidence 0.26 Published 2007 Journal J Med Case Reports Section Body Doc Link PMC1950516 Disease Relevance 0.49 Pain Relevance 0.07

General Comments

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