INT132969

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.27
First Reported 2006
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 8
Disease Relevance 10.84
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
epithelial cells 1
keratinocyte 1
HPV18I1 (Homo sapiens)
Pain Link Frequency Relevance Heat
addiction 10 97.02 Very High Very High Very High
imagery 15 5.00 Very Low Very Low Very Low
analgesia 5 5.00 Very Low Very Low Very Low
Inflammation 5 5.00 Very Low Very Low Very Low
Bioavailability 5 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
headache 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Papillomavirus Infection 1739 100.00 Very High Very High Very High
Cervical Cancer 220 99.68 Very High Very High Very High
Infection 505 98.76 Very High Very High Very High
Injury 7 91.76 High High
Cancer 112 78.28 Quite High
Death 7 73.16 Quite High
Recurrence 29 61.04 Quite High
Apoptosis 7 52.84 Quite High
Uterine Cancer 2 51.60 Quite High
Stress 5 50.84 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In analytical sensitivity studies, fewer than 100 genome copies of HPV1a and 2a were detected, and fewer than 1000 copies of HPV4 were detected.
Gene_expression (detected) of HPV4
1) Confidence 0.27 Published 2006 Journal J. Clin. Virol. Section Body Doc Link 16420985 Disease Relevance 0.06 Pain Relevance 0
In low-grade squamous intraepithelial lesions (LSIL), high-risk HPV DNA can be detected in 30 to 100% of cases in different studies [17].
Gene_expression (detected) of HPV associated with papillomavirus infection
2) Confidence 0.01 Published 2008 Journal Infect Agent Cancer Section Body Doc Link PMC2628336 Disease Relevance 2.54 Pain Relevance 0
High-risk HPV DNA is virtually detectable in all cervical cancers [15].
Gene_expression (detectable) of HPV associated with cervical cancer and papillomavirus infection
3) Confidence 0.01 Published 2008 Journal Infect Agent Cancer Section Body Doc Link PMC2628336 Disease Relevance 2.21 Pain Relevance 0
Our further testing with wild type HPV16 virions confirmed that one round of the cell cycle through M phase is sufficient for HPV early gene expression (Figure S2).
Gene_expression (expression) of HPV associated with papillomavirus infection
4) Confidence 0.01 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2642596 Disease Relevance 0.80 Pain Relevance 0
Beyond the potential mechanisms of cell cycle dependence suggested above, host genes or gene combinations specifically expressed only in early mitosis might have essential roles for HPV entry steps and/or HPV early gene expression.
Gene_expression (expression) of HPV associated with addiction and papillomavirus infection
5) Confidence 0.01 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2642596 Disease Relevance 1.28 Pain Relevance 0.05
HPV early genes are expressed throughout this life cycle, while late capsid genes L1 and L2 are only expressed in terminally differentiated epithelial cells.
Gene_expression (expressed) of HPV in epithelial cells associated with papillomavirus infection
6) Confidence 0.01 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2642596 Disease Relevance 1.50 Pain Relevance 0
Consistent with this premise, HPV gene expression levels were further enhanced when the cell cycle was released for progressively longer periods before G2 arrest, eventually reaching levels well above the control “no arrest” conditions (Figure 4).
Gene_expression (expression) of HPV associated with papillomavirus infection
7) Confidence 0.01 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2642596 Disease Relevance 0.93 Pain Relevance 0
The tight link between keratinocyte differentiation and the HPV life cycle has made large scale production of mature infectious HPV particles difficult, greatly restricting studies of the mechanisms of natural HPV infection [8],[9].
Gene_expression (production) of HPV in keratinocyte associated with papillomavirus infection and infection
8) Confidence 0.01 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2642596 Disease Relevance 1.53 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox