INT133076

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Context Info
Confidence 0.38
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.95

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transducer activity (STAT6, OPRM1) Golgi apparatus (OPRM1) endoplasmic reticulum (OPRM1)
cytoplasm (STAT6) cytosol (STAT6) signal transduction (STAT6)
STAT6 (Homo sapiens)
OPRM1 (Homo sapiens)
Pain Link Frequency Relevance Heat
opioid receptor 9 100.00 Very High Very High Very High
Cannabinoid 8 95.20 Very High Very High Very High
mu opioid receptor 1 84.80 Quite High
antagonist 2 82.32 Quite High
Cannabinoid receptor 2 75.00 Quite High
agonist 1 75.00 Quite High
Morphine 1 72.80 Quite High
Opioid 2 57.44 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Further experiments demonstrate that interleukin-4 then induces phosphorylation of STAT6, which directly transactivates the mu-opioid receptor gene.
STAT6 Positive_regulation (transactivates) of mu-opioid receptor associated with opioid receptor
1) Confidence 0.38 Published 2006 Journal Mol. Pharmacol. Section Abstract Doc Link 16434616 Disease Relevance 0 Pain Relevance 0.95

General Comments

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