INT133176

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Context Info
Confidence 0.01
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.24
Pain Relevance 0.86

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Mastl, Il12a) mitosis (Mastl) extracellular space (Il12a)
extracellular region (Il12a) nucleus (Mastl) cytoskeleton (Mastl)
Anatomy Link Frequency
dendritic cells 2
Mastl (Mus musculus)
Il12a (Mus musculus)
Pain Link Frequency Relevance Heat
Delta-9-tetrahydrocannabinol 9 100.00 Very High Very High Very High
antagonist 2 98.32 Very High Very High Very High
Cannabinoid receptor 4 96.60 Very High Very High Very High
cytokine 3 95.40 Very High Very High Very High
Cannabinoid 2 89.88 High High
Endocannabinoid 1 72.64 Quite High
qutenza 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Targeted Disruption 1 91.60 High High
Bordatella Infection 1 82.64 Quite High
Infection 1 68.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results suggest that THC-induced suppression of serum IL-12 is partly due to a suppression of IL-12 production by dendritic cells and that G(i) signaling and cannabinoid receptors, but not TRPV1, are involved in this suppressive effect.
Regulation (due) of THC Negative_regulation (suppression) of IL-12 in dendritic cells associated with cannabinoid receptor and delta-9-tetrahydrocannabinol
1) Confidence 0.01 Published 2006 Journal Eur. J. Pharmacol. Section Abstract Doc Link 16443217 Disease Relevance 0.24 Pain Relevance 0.86

General Comments

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