INT133231

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Context Info
Confidence 0.39
First Reported 2005
Last Reported 2010
Negated 1
Speculated 4
Reported most in Body
Documents 18
Total Number 22
Disease Relevance 5.02
Pain Relevance 4.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (PYCARD) signal transduction (PYCARD) intracellular (PYCARD)
cytoplasm (PYCARD)
Anatomy Link Frequency
bar 1
muscles 1
lobe 1
lung 1
cortex 1
PYCARD (Homo sapiens)
Pain Link Frequency Relevance Heat
Transcranial magnetic stimulation 2038 100.00 Very High Very High Very High
depression 30 99.96 Very High Very High Very High
Dopamine 19 88.00 High High
primary somatosensory cortex 6 86.80 High High
Glutamate 22 85.28 High High
antidepressant 14 83.56 Quite High
headache 4 82.00 Quite High
Pain 4 81.20 Quite High
dexamethasone 1 77.04 Quite High
Migraine 6 75.40 Quite High
Disease Link Frequency Relevance Heat
Depression 32 99.96 Very High Very High Very High
Parkinson's Disease 6 99.84 Very High Very High Very High
Cancer 1 99.84 Very High Very High Very High
Reprotox - General 1 1 98.32 Very High Very High Very High
Hyperplasia 1 97.56 Very High Very High Very High
Skin Cancer 1 97.52 Very High Very High Very High
Tinnitus 84 95.72 Very High Very High Very High
Cognitive Disorder 49 95.48 Very High Very High Very High
Otitis Media 71 93.92 High High
Apoptosis 8 93.48 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In this work we have investigated the effects of various rTMS protocols on performance on tasks that require the observer to discriminate the orientation of a visual pattern.
Spec (investigated) Regulation (effects) of rTMS
1) Confidence 0.39 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2860988 Disease Relevance 0 Pain Relevance 0
Per TW, RTdif is shown in a bar graph for PPC and MFG separately, alongside the RTdif for the time control condition (TC), and the average RTdif for the SHAM TMS control condition (SC).
Regulation (control) of SHAM TMS in bar associated with transcranial magnetic stimulation
2) Confidence 0.38 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2789405 Disease Relevance 0 Pain Relevance 0.28
Further, additional control was offered by our use of multiple tasks (controlling for task-specificity), sites (controlling for regional specificity), a time window beyond average response times (time control: similar to no-TMS but with the same anticipation of TMS pulses), and multiple time windows (controlling for temporal specificity).
Regulation (controlling) of TMS associated with transcranial magnetic stimulation
3) Confidence 0.38 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2789405 Disease Relevance 0 Pain Relevance 0.34
On the assumption that our localization methods identified the same PPC and MFG, our data show that MFG is a functionally relevant region, which by extension suggests that the parietal TMS-induced remote BOLD effects in MFG revealed by Sack et al. [21] may also have been functionally relevant.
Regulation (effects) of TMS-induced in parietal associated with transcranial magnetic stimulation
4) Confidence 0.38 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2789405 Disease Relevance 0 Pain Relevance 0.43
There have been several meta-analyses of these placebo-controlled trials of rTMS for major depression.
Spec (analyses) Regulation (controlled) of rTMS associated with depression
5) Confidence 0.38 Published 2006 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2671781 Disease Relevance 0.31 Pain Relevance 0.36
Signal detection theory was applied to analyze the effect of TMS intensity on performance in the somatosensory task.
Spec (analyze) Regulation (effect) of TMS associated with transcranial magnetic stimulation
6) Confidence 0.37 Published 2010 Journal Neuropsychologia Section Body Doc Link PMC2956832 Disease Relevance 0 Pain Relevance 0.20
For instance, stimulating motor cortex in one hemisphere with a pulse of transcranial magnetic stimulation (TMS) can inhibit the response of the contralateral motor cortex to TMS several milliseconds later (e.g., Daskalakis, Christensen, Fitzgerald, Roshan, & Chen, 2002; Ferbert et al., 1992).
Regulation (response) of TMS in cortex associated with transcranial magnetic stimulation
7) Confidence 0.37 Published 2010 Journal Neuropsychologia Section Body Doc Link PMC2956832 Disease Relevance 0 Pain Relevance 0.24
For each comparison, Fig. 2 displays the superimposition of TMS-evoked potentials at the sensor level (A,B) as well as the cortical current density maps (C) and the temporal profile of current density integrated over the left frontal and occipital lobules (D).
Regulation (superimposition) of TMS-evoked associated with transcranial magnetic stimulation
8) Confidence 0.30 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2858649 Disease Relevance 0 Pain Relevance 0.19
Similarly, other factors, such as EEG sensors positioning, coil temperature, calibration of amplifiers, etc., may, if not adequately controlled for, affect the repeatability of TMS-evoked potentials.
Regulation (repeatability) of TMS-evoked associated with transcranial magnetic stimulation
9) Confidence 0.30 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2858649 Disease Relevance 0 Pain Relevance 0.24
In addition, TMS coil orientation has been shown to affect the motor threshold [41], the degree of selectivity when stimulating different peripheral muscles [42] and even cognitive functions [43].
Regulation (affect) of TMS in muscles associated with cognitive disorder and transcranial magnetic stimulation
10) Confidence 0.30 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2858649 Disease Relevance 0.10 Pain Relevance 0.13
Furthermore, it was shown that the promoter region of ASC is often hypermethylated in tumor cells such as breast, lung, and prostate cancer and melanoma [28].
Regulation (hypermethylated) of ASC in lung associated with cancer, skin cancer and reprotox - general 1
11) Confidence 0.27 Published 2008 Journal Molecular Vision Section Body Doc Link PMC2526096 Disease Relevance 0.75 Pain Relevance 0
Third, and perhaps most important: to directly address the issue of potential differences in TMS effects between PPC and MFG, we statistically analyzed the differences between the two stimulation sites per time window using paired samples t-tests (two-tailed).
Regulation (effects) of TMS associated with transcranial magnetic stimulation
12) Confidence 0.23 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2789405 Disease Relevance 0 Pain Relevance 0.36
Of the participants, 14 (30,4 %) demonstrated no placebo effect on both tonic and burst rTMS, 9 (19,6%) did have a placebo suppression, and 23 (50%) showed no suppressive response to either burst nor tonic rTMS.
Neg (no) Regulation (effect) of rTMS
13) Confidence 0.23 Published 2007 Journal International Journal of Medical Sciences Section Body Doc Link PMC2016868 Disease Relevance 0.39 Pain Relevance 0
There was a significant main effect of TMS level on sensitivity, such that high- vs. low-intensity TMS now impaired performance [F(1,68) = 4.71, p = 0.03, Fig. 6], quite unlike the facilitation of detection found ipsilaterally in Experiment 1.
Regulation (effect) of TMS associated with transcranial magnetic stimulation
14) Confidence 0.22 Published 2010 Journal Neuropsychologia Section Body Doc Link PMC2956832 Disease Relevance 0 Pain Relevance 0.20
All published, sham-controlled rTMS depression trials were reviewed for reported side-effects and outcomes of formal neuropsychological testing.
Regulation (controlled) of rTMS associated with depression
15) Confidence 0.20 Published 2008 Journal Int. J. Neuropsychopharmacol. Section Abstract Doc Link 17880752 Disease Relevance 0.65 Pain Relevance 0.40
The Asc oxidation rate was determined by measuring changes in the Asc peak at 266 nm.
Spec (determined) Regulation (changes) of Asc
16) Confidence 0.18 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3001466 Disease Relevance 0 Pain Relevance 0
Three TMS targets were identified on individual MRIs in the left occipital lobe (Brodmann's area - BA19), the left parietal lobe (BA7) and the left frontal lobe (BA6).
Regulation (targets) of TMS in lobe associated with transcranial magnetic stimulation
17) Confidence 0.18 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2858649 Disease Relevance 0.33 Pain Relevance 0.23
To compare the cumulative and daily doses of the different antipsychotics and to explore the influence of this medication on TMS parameters, chlorpromazine (CPZ) equivalents were calculated (as suggested by reviews and studies focusing on second generation antipsychotics, e.g., Woods 2003).
Regulation (influence) of TMS associated with transcranial magnetic stimulation
18) Confidence 0.16 Published 2009 Journal Psychopharmacology (Berl) Section Body Doc Link PMC2806533 Disease Relevance 0.77 Pain Relevance 0.38
Noticeable changes were observed in the TMs of the inoculated rats compared to the control animal using both the otoscopy images and LCI data, even though most inoculated animals did not appear sick during the inoculation period.
Regulation (changes) of TMs
19) Confidence 0.05 Published 2010 Journal Biomedical Optics Express Section Body Doc Link PMC3018087 Disease Relevance 0.15 Pain Relevance 0
CONCLUSION: SEP and TMS-MEP are very sensitive to SCI, in particular, the change of amplitude is more sensitive then the latency change and can more accurately reflect the degree of SCI.
Regulation (sensitive) of TMS-MEP
20) Confidence 0.04 Published 2008 Journal Zhonghua Yi Xue Za Zhi Section Body Doc Link 18683688 Disease Relevance 0 Pain Relevance 0

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