INT133256

Context Info Confidence 0.04 First Reported 2006 Last Reported 2006 Negated 0 Speculated 1 Reported most in Abstract Documents 1 Total Number 2 Disease Relevance 1.50 Pain Relevance 0.07

cytoskeletal protein binding (Anxa2) extracellular region (Anxa2) proteinaceous extracellular matrix (Anxa2) plasma membrane (Anxa2) protein complex (Anxa2) cytoplasm (Anxa2)

Anatomy Link Frequency pancreas 1 Anxa2 (Mus musculus)

Pain Link Frequency Relevance Heat Chronic pancreatitis 2 72.64

Disease Link Frequency Relevance Heat Fibrosis 2 99.08 Pancreatic Cancer 6 98.80 Adenocarcinoma 8 94.16 Solid Tumor 2 85.04 Pancreatitis 2 72.64 Cancer 6 61.04 Necrosis 2 60.48

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The mRNA and protein levels of TNC and of annexin II were analysed in pancreatic tissues by DNA array, quantitative reverse transcriptase-polymerase chain reaction (QRT-PCR) and immunohistochemistry.

Spec (analysed) Transcription (levels) of annexin II

1) Confidence 0.04 Published 2006 Journal J. Pathol. Section Abstract Doc Link 16450333 Disease Relevance 0.59 Pain Relevance 0

TNC and annexin II mRNA levels were significantly higher in pancreatic cancer tissues than in the normal pancreas.

Transcription (levels) of annexin II in pancreas associated with pancreatic cancer

2) Confidence 0.04 Published 2006 Journal J. Pathol. Section Abstract Doc Link 16450333 Disease Relevance 0.90 Pain Relevance 0.07

General Comments

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