INT133589

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Context Info
Confidence 0.25
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 2.84
Pain Relevance 0.61

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
arm 1
Pol (Mus musculus)
Pain Link Frequency Relevance Heat
tolerance 1 98.28 Very High Very High Very High
addiction 12 92.00 High High
palliative 4 88.40 High High
Angina 3 64.68 Quite High
withdrawal 1 62.08 Quite High
headache 3 61.44 Quite High
cva 1 60.28 Quite High
Pain 2 43.72 Quite Low
alcohol 1 38.88 Quite Low
anesthesia 4 31.20 Quite Low
Disease Link Frequency Relevance Heat
Cytomegalovirus Infection 200 99.98 Very High Very High Very High
Colon Cancer 3 93.80 High High
Infection 156 91.40 High High
Acquired Immune Deficiency Syndrome Or Hiv Infection 66 90.56 High High
Adenocarcinoma 7 84.64 Quite High
Cancer 33 82.04 Quite High
Congenital Anomalies 4 71.32 Quite High
Angina 3 64.68 Quite High
Headache 3 61.44 Quite High
Dizziness 1 60.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The COBAS amplicor CMV monitor test was adapted to measure the HCMV pol DNA copy numbers in culture supernatants, using the COBAS AMPLICOR Analyzer (Roche Molecular Systems).
Negative_regulation (numbers) of pol associated with cytomegalovirus infection
1) Confidence 0.25 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2673691 Disease Relevance 1.03 Pain Relevance 0
It was flawless in preventing a POL in a patient with an IOL, provided of course that the IOL result was acted on.
Negative_regulation (preventing) of POL
2) Confidence 0.24 Published 2007 Journal BMC Surg Section Body Doc Link PMC1950862 Disease Relevance 0.18 Pain Relevance 0.06
In order to minimise the risk of RCR production, an improved vector system was designed by segregating the gag/pol and env genes present on the packaging construct, onto discrete expression units, Figure 4.
Negative_regulation (segregating) of pol
3) Confidence 0.17 Published 2010 Journal Int Arch Med Section Body Doc Link PMC3016243 Disease Relevance 0 Pain Relevance 0
However, if PoL and QoL outcomes of the experimental arm were opposite, which was the case in 13 out of 28 trials, the authors generally based their conclusion on PoL outcomes.
Negative_regulation (opposite) of PoL in arm
4) Confidence 0.12 Published 2006 Journal Eur. J. Cancer Section Abstract Doc Link 16481158 Disease Relevance 0.25 Pain Relevance 0.22
Previous studies showed that defective pol ?
Negative_regulation (defective) of pol
5) Confidence 0.01 Published 2010 Journal J Transl Med Section Abstract Doc Link PMC3003639 Disease Relevance 0.36 Pain Relevance 0.05
0.001; Fisher's exact test) with only 2 vaccinees exhibiting Gag/Pol responses in the absence of an Env response.
Negative_regulation (exhibiting) of Pol
6) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2981570 Disease Relevance 1.02 Pain Relevance 0.28

General Comments

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