INT133650

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Context Info
Confidence 0.35
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Title
Documents 1
Total Number 2
Disease Relevance 2.70
Pain Relevance 1.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Epo, TNF) extracellular region (Epo, TNF) signal transduction (TNF)
aging (Epo) plasma membrane (TNF) intracellular (TNF)
Anatomy Link Frequency
peripheral nerve 1
Epo (Rattus norvegicus)
TNF (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 6 98.84 Very High Very High Very High
Peripheral nerve injury 2 97.68 Very High Very High Very High
Sciatic nerve 2 96.36 Very High Very High Very High
Neuropathic pain 2 91.84 High High
Inflammation 2 90.12 High High
cytokine 2 89.60 High High
Lasting pain 2 32.04 Quite Low
Disease Link Frequency Relevance Heat
Wallerian Degeneration 4 99.92 Very High Very High Very High
Pain 8 98.84 Very High Very High Very High
Nervous System Injury 4 98.24 Very High Very High Very High
Injury 14 95.28 Very High Very High Very High
Neuropathic Pain 2 91.84 High High
INFLAMMATION 2 90.12 High High
Cancer 2 88.84 High High
Necrosis 2 88.60 High High
Death 4 43.04 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Systemically or locally administered rhEpo decreased TNF-alpha mRNA, compared with that observed in untreated animals.
rhEpo Negative_regulation (decreased) of TNF-alpha
1) Confidence 0.35 Published 2006 Journal Eur. J. Neurosci. Section Abstract Doc Link 16487143 Disease Relevance 1.33 Pain Relevance 0.50
Erythropoietin reduces Schwann cell TNF-alpha, Wallerian degeneration and pain-related behaviors after peripheral nerve injury.
Erythropoietin Negative_regulation (reduces) of TNF-alpha in peripheral nerve associated with pain, nervous system injury, wallerian degeneration and peripheral nerve injury
2) Confidence 0.35 Published 2006 Journal Eur. J. Neurosci. Section Title Doc Link 16487143 Disease Relevance 1.38 Pain Relevance 0.54

General Comments

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