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Context Info
Confidence 0.50
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.25
Pain Relevance 0.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Epo, TNF) extracellular region (Epo, TNF) signal transduction (TNF)
aging (Epo) plasma membrane (TNF) intracellular (TNF)
Anatomy Link Frequency
Schwann cells 1
Epo (Rattus norvegicus)
TNF (Homo sapiens)
Pain Link Frequency Relevance Heat
Lasting pain 1 93.32 High High
Pain 3 75.00 Quite High
Peripheral nerve injury 1 75.00 Quite High
Neuropathic pain 1 58.60 Quite High
cytokine 1 50.48 Quite High
Inflammation 1 50.08 Quite High
Sciatic nerve 1 43.88 Quite Low
Disease Link Frequency Relevance Heat
Death 2 96.88 Very High Very High Very High
Injury 7 93.96 High High
Pain 4 93.32 High High
Nervous System Injury 2 75.00 Quite High
Wallerian Degeneration 2 75.00 Quite High
Neuropathic Pain 1 58.60 Quite High
Necrosis 1 51.44 Quite High
Cancer 1 51.08 Quite High
INFLAMMATION 1 50.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results indicated that rhEpo regulates TNF-alpha by multiple mechanisms; rhEpo regulates TNF-alpha mRNA expression by Schwann cells but also may directly counteract TNF-alpha signaling pathways that lead to injury, chronic pain and/or death.
rhEpo Regulation (regulates) of TNF-alpha in Schwann cells associated with lasting pain, injury and death
1) Confidence 0.50 Published 2006 Journal Eur. J. Neurosci. Section Abstract Doc Link 16487143 Disease Relevance 1.25 Pain Relevance 0.38

General Comments

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