INT13381

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Context Info
Confidence 0.44
First Reported 1991
Last Reported 1996
Negated 1
Speculated 1
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0
Pain Relevance 0.46

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (YY1) chromosome organization (YY1) RNA binding (YY1)
plasma membrane (YY1) nucleus (YY1) intracellular (YY1)
YY1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Opioid 3 97.28 Very High Very High Very High
Kappa opioid receptor 1 94.56 High High
opioid receptor 3 88.16 High High
mu opioid receptor 2 75.00 Quite High
Enkephalin 4 25.00 Low Low
Analgesic 1 25.00 Low Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The length of the hydrophilic spacer does not affect the affinity for delta receptors, whereas shorter spacer length increases affinity for mu and even more so for kappa receptors.
Neg (not) Regulation (affect) of delta Neg (not) Binding (affinity) of
1) Confidence 0.44 Published 1991 Journal Int. J. Pept. Protein Res. Section Abstract Doc Link 1668098 Disease Relevance 0 Pain Relevance 0.39
The sensitivity of mu and delta receptor binding to dithiothreitol and N-ethylmaleimide was examined to probe receptor structure and function.
Regulation (sensitivity) of delta Spec (examined) Binding (binding) of
2) Confidence 0.26 Published 1996 Journal J. Biol. Chem. Section Abstract Doc Link 8621408 Disease Relevance 0 Pain Relevance 0.07

General Comments

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