INT133819

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Context Info
Confidence 0.61
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.64
Pain Relevance 0.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (CXCR2) plasma membrane (CXCR2) intracellular (CXCR2)
signal transducer activity (CXCR2)
Anatomy Link Frequency
endometrium 1
neutrophils 1
CXCR2 (Homo sapiens)
Pain Link Frequency Relevance Heat
chemokine 16 95.96 Very High Very High Very High
Inflammation 13 92.24 High High
cytokine 4 85.28 High High
opioid receptor 19 85.04 High High
antagonist 13 83.76 Quite High
narcan 3 82.88 Quite High
Dismenorea 2 50.00 Quite Low
Inflammatory marker 2 37.60 Quite Low
Inflammatory response 3 30.64 Quite Low
nud 5 23.52 Low Low
Disease Link Frequency Relevance Heat
Gastritis 5 97.84 Very High Very High Very High
Duodenal Ulcer 3 97.28 Very High Very High Very High
Infection 40 95.60 Very High Very High Very High
Gastroesophageal Reflux Disease 76 93.52 High High
INFLAMMATION 19 92.24 High High
Dysmenorrhea 2 78.96 Quite High
Disease 14 62.72 Quite High
Bordatella Infection 8 55.36 Quite High
Ulcers 14 50.00 Quite Low
Sprains And Strains 13 33.64 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
MAIN OUTCOME MEASURE(S): Microscopic evaluation to assess the presence and localization of CXCR1 and CXCR2 throughout the menstrual cycle in both eutopic endometrial and adenomyotic tissues of women with adenomyosis and compare it with normal endometrium.
Localization (localization) of CXCR2 in endometrium
1) Confidence 0.61 Published 2006 Journal Fertil. Steril. Section Body Doc Link 16500343 Disease Relevance 0.08 Pain Relevance 0
In contrast, anti-VSV-G immunoreactivity was only detected following treatment of the cells with doxycycline (Figure 7A) and merging of the images indicated co-localization of VSV-G–hCXCR2 and FLAG–hDOP at the cell surface (Figure 7A).
Localization (localization) of hCXCR2
2) Confidence 0.21 Published 2008 Journal Biochemical Journal Section Body Doc Link PMC2474558 Disease Relevance 0.06 Pain Relevance 0.16
But, their expression is dependent on the corresponding expression of their receptors (CXCR1 and CXCR2) on neutrophils.95 IL-8 may influence development of gastritis and duodenal ulcer in patients with H. pylori infection.96,97
Localization (receptors) of CXCR2 in neutrophils associated with duodenal ulcer, gastritis and infection
3) Confidence 0.08 Published 2010 Journal Journal of Neurogastroenterology and Motility Section Body Doc Link PMC2912116 Disease Relevance 1.50 Pain Relevance 0.21

General Comments

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