INT133823

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Context Info
Confidence 0.64
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 7
Total Number 7
Disease Relevance 6.81
Pain Relevance 1.52

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
ankle 2
leg 1
pad (Mus musculus)
Pain Link Frequency Relevance Heat
Restless leg syndrome 8 100.00 Very High Very High Very High
Action potential 2 100.00 Very High Very High Very High
Pain 15 97.52 Very High Very High Very High
gABA 4 95.40 Very High Very High Very High
Dorsal horn 3 91.88 High High
c fibre 1 86.88 High High
Hyperalgesia 14 83.44 Quite High
Neuropathic pain 18 74.88 Quite High
Spinal cord 26 73.24 Quite High
spinal dorsal horn 1 70.96 Quite High
Disease Link Frequency Relevance Heat
Peripheral Arterial Disease 86 100.00 Very High Very High Very High
Increased Venous Pressure Under Development 23 100.00 Very High Very High Very High
Pain 14 97.52 Very High Very High Very High
Asymptomatic Diseases 1 93.52 High High
Diabetes Mellitus 24 91.72 High High
Stroke 2 90.36 High High
Nociception 7 90.16 High High
Heart Disease 2 90.04 High High
Disease 11 89.24 High High
Nicotine Addiction 5 87.12 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the second part, significant PAD was found in 111 cases corresponding to a prevalence of 12.2%.
Localization (found) of PAD associated with peripheral arterial disease
1) Confidence 0.64 Published 2008 Journal Clin Physiol Funct Imaging Section Abstract Doc Link 18803641 Disease Relevance 1.10 Pain Relevance 0.08
The ankle brachial index based on measurements with an oscillometric device was shown reliable in the exclusion of PAD, thereby fulfilling an important criterion for the use in screening.
Localization (exclusion) of PAD in ankle associated with peripheral arterial disease
2) Confidence 0.60 Published 2008 Journal Clin Physiol Funct Imaging Section Abstract Doc Link 18803641 Disease Relevance 1.07 Pain Relevance 0.09
The presence of PAD was assessed by ankle brachial index (ABI) in 345 ambulatory osteoporotic postmenopausal women, and in 360 community-based, age- and race-matched postmenopausal women with normal bone mineral density (BMD) (control group).
Localization (presence) of PAD in ankle associated with peripheral arterial disease
3) Confidence 0.48 Published 2006 Journal J. Bone Miner. Metab. Section Abstract Doc Link 16502119 Disease Relevance 0.52 Pain Relevance 0
Lower extremity peripheral arterial disease (PAD) and musculoskeletal conditions both produce symptoms of leg pain, and may coexist.
Localization (disease) of PAD in leg associated with pain and peripheral arterial disease
4) Confidence 0.41 Published 2008 Journal Vasc Med Section Abstract Doc Link 18687760 Disease Relevance 0.98 Pain Relevance 0.33
The office-based assessment of PAD is limited by the need of specialized equipment (handheld Doppler), its cost (rupees 15 – 20 thousand), the time required for performing the test (at least 20 minutes), and the skill of the performer.[110]
Localization (assessment) of PAD associated with peripheral arterial disease
5) Confidence 0.14 Published 2010 Journal International Journal of Diabetes in Developing Countries Section Body Doc Link PMC2878698 Disease Relevance 1.29 Pain Relevance 0
Participants (n=21) with an appropriate history of PAD and intermittent claudication (IC) volunteered for this study and were randomly allocated to either a control group (CPAD-IC) (n=11), which received normal medical therapy and a treatment group (TPAD-IC) (n=10), which received normal medical therapy treatment and a 12month supervised exercise program.
Localization (allocated) of PAD associated with restless leg syndrome and peripheral arterial disease
6) Confidence 0.09 Published 2009 Journal Hum Mov Sci Section Abstract Doc Link 19435644 Disease Relevance 0.82 Pain Relevance 0.45
PAD shunts the magnitude of incoming action potentials and decreases excitatory amino release at the primary afferent central terminals [3,4].
Localization (release) of PAD associated with action potential and peripheral arterial disease
7) Confidence 0.07 Published 2008 Journal Mol Pain Section Body Doc Link PMC2561007 Disease Relevance 1.04 Pain Relevance 0.57

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