INT133870

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Context Info
Confidence 0.35
First Reported 2006
Last Reported 2010
Negated 0
Speculated 1
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.41
Pain Relevance 1.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (LAMB1) extracellular region (LAMB1) cell adhesion (LAMB1)
structural molecule activity (LAMB1) enzyme binding (LAMB1)
Anatomy Link Frequency
mesenchyme 2
embryonic kidney 2
LAMB1 (Homo sapiens)
Pain Link Frequency Relevance Heat
sodium channel 11 100.00 Very High Very High Very High
bDMF 12 96.80 Very High Very High Very High
Neuropathic pain 2 93.64 High High
Pain 2 88.16 High High
tetrodotoxin 2 86.64 High High
Root ganglion neuron 2 82.16 Quite High
Central nervous system 1 76.32 Quite High
imagery 1 72.16 Quite High
Nerve growth factor 6 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neuropathic Pain 2 93.64 High High
Pain 2 88.16 High High
Ganglion Cysts 2 81.76 Quite High
Adhesions 5 5.00 Very Low Very Low Very Low
Body Weight 1 5.00 Very Low Very Low Very Low
Nervous System Injury 1 5.00 Very Low Very Low Very Low
Injury 1 5.00 Very Low Very Low Very Low
Leukemia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Only morphogen BMP2 appeared overexpressed in mesenchyme, whereas GPI, LAMB1, Meteorin and TGF?
Spec (appeared) Positive_regulation (overexpressed) of Gene_expression (overexpressed) of LAMB1 in mesenchyme
1) Confidence 0.35 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3004953 Disease Relevance 0 Pain Relevance 0.08
To facilitate the identification of NaV1.8-specific inhibitors, we stably expressed the human NaV1.8 channel together with the auxiliary human beta1 subunit (NaV beta1) in human embryonic kidney 293 cells.
Positive_regulation (expressed) of Gene_expression (expressed) of beta1 subunit in embryonic kidney associated with sodium channel
2) Confidence 0.02 Published 2006 Journal Assay Drug Dev Technol Section Abstract Doc Link 16506887 Disease Relevance 0.41 Pain Relevance 1.06

General Comments

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