INT133941

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Context Info
Confidence 0.02
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.76

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (ARFGEF1) nucleolus (ARFGEF1) plasma membrane (OPRK1)
nucleus (ARFGEF1) intracellular (ARFGEF1) signal transducer activity (OPRK1)
ARFGEF1 (Homo sapiens)
OPRK1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Kappa opioid receptor 8 100.00 Very High Very High Very High
Potency 3 99.24 Very High Very High Very High
opioid receptor 2 87.24 High High
Dynorphin 4 80.48 Quite High
Endogenous opioid 1 76.12 Quite High
Nucleus accumbens 1 62.88 Quite High
Hippocampus 1 60.00 Quite High
Pain 3 25.00 Low Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast, Big Dyn activated G proteins through KOR with much greater potency, efficacy and selectivity than other dynorphins.
Big Positive_regulation (activated) of KOR associated with kappa opioid receptor and potency
1) Confidence 0.02 Published 2006 Journal J. Neurochem. Section Abstract Doc Link 16515546 Disease Relevance 0 Pain Relevance 0.76

General Comments

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