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Context Info
Confidence 0.00
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.73

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plasma membrane (DNM2, OPRL1) enzyme binding (DNM2) GTPase activity (DNM2)
signal transducer activity (OPRL1) cytoplasm (DNM2) cytosol (DNM2)
DNM2 (Homo sapiens)
OPRL1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Kappa opioid receptor 8 100.00 Very High Very High Very High
Dynorphin 4 100.00 Very High Very High Very High
opioid receptor 2 100.00 Very High Very High Very High
Endogenous opioid 1 96.80 Very High Very High Very High
Potency 3 71.60 Quite High
Nucleus accumbens 1 36.00 Quite Low
Hippocampus 1 33.12 Quite Low
Pain 3 25.00 Low Low


Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Here, we characterized interactions of big dynorphin (Big Dyn), a 32-amino acid prodynorphin-derived peptide consisting of Dyn A and Dyn B, with human KOR, mu- (hMOR) and delta- (hDOR) opioid receptors and opioid receptor-like receptor 1 (hORL1) expressed in cells transfected with respective cDNA.
Dyn Binding (interactions) of hORL1 associated with dynorphin, kappa opioid receptor and opioid receptor
1) Confidence 0.00 Published 2006 Journal J. Neurochem. Section Abstract Doc Link 16515546 Disease Relevance 0 Pain Relevance 0.73

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