INT133948

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Context Info
Confidence 0.09
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.62

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (ARFGEF1) nucleolus (ARFGEF1) nucleus (ARFGEF1)
intracellular (ARFGEF1) cytoplasm (ARFGEF1)
Anatomy Link Frequency
neurons 1
ARFGEF1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Potency 3 96.96 Very High Very High Very High
Hippocampus 1 94.76 High High
Nucleus accumbens 1 93.56 High High
Kappa opioid receptor 8 89.60 High High
Dynorphin 4 75.00 Quite High
opioid receptor 2 59.96 Quite High
Endogenous opioid 1 48.84 Quite Low
Pain 3 25.00 Low Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The presence in the brain implies that Big Dyn, along with other dynorphins, is processed from prodynorphin and secreted from neurons.
Localization (secreted) of Big in neurons
1) Confidence 0.09 Published 2006 Journal J. Neurochem. Section Abstract Doc Link 16515546 Disease Relevance 0 Pain Relevance 0.62

General Comments

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