INT133974

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Context Info
Confidence 0.37
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.52
Pain Relevance 0.59

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Pou1f1) DNA binding (Pou1f1) transcription factor binding (Pou1f1)
cytoplasm (Pou1f1)
Anatomy Link Frequency
Pit 2
endothelial cell 1
Pou1f1 (Mus musculus)
Pain Link Frequency Relevance Heat
opiate 2 80.72 Quite High
cva 2 80.32 Quite High
Pain 2 79.96 Quite High
Central nervous system 2 79.32 Quite High
Neuropeptide 4 75.32 Quite High
anesthesia 1 5.00 Very Low Very Low Very Low
Osteoarthritis 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Anaemia 14 85.24 High High
Hemorrhage 2 80.32 Quite High
Pain 2 79.96 Quite High
Apoptosis 14 69.04 Quite High
Death 5 48.08 Quite Low
Embryonic Lethality 8 5.00 Very Low Very Low Very Low
Calcification 6 5.00 Very Low Very Low Very Low
Osteoporosis 5 5.00 Very Low Very Low Very Low
Congenital Anomalies 4 5.00 Very Low Very Low Very Low
Hematological Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Histological examination and anti-PECAM-1 staining of endothelial cell of PiT1?
PiT1 Binding (endothelial cell) of in endothelial cell
1) Confidence 0.37 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2818845 Disease Relevance 0.36 Pain Relevance 0.04
Electromobility shift assays revealed one region that may interact with the homeobox proteins Oct-1, PDX1, Pit-1 and MEIS and two consensus DRE sites that bind a nuclear protein, which was identified as the downstream regulatory element antagonistic modulator DREAM by supershift assays.
Pit-1 Binding (interact) of in Pit
2) Confidence 0.08 Published 2006 Journal Peptides Section Abstract Doc Link 16515822 Disease Relevance 0.08 Pain Relevance 0.28
Electromobility shift assays revealed one region that may interact with the homeobox proteins Oct-1, PDX1, Pit-1 and MEIS and two consensus DRE sites that bind a nuclear protein, which was identified as the downstream regulatory element antagonistic modulator DREAM by supershift assays.
Pit-1 Binding (bind) of in Pit
3) Confidence 0.08 Published 2006 Journal Peptides Section Abstract Doc Link 16515822 Disease Relevance 0.08 Pain Relevance 0.27

General Comments

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