INT13398

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Context Info
Confidence 0.44
First Reported 1991
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 0.60
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (DMD) cytoskeleton (DMD) nucleus (DMD)
cytoplasm (DMD)
Anatomy Link Frequency
muscle 6
eyes 2
hip 2
DMD (Homo sapiens)
Pain Link Frequency Relevance Heat
cva 1 93.20 High High
ketamine 2 84.20 Quite High
Spinal cord 2 80.64 Quite High
anesthesia 2 47.68 Quite Low
tetrodotoxin 1 26.72 Quite Low
Pain 2 24.04 Low Low
Inflammation 2 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
beta blocker 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Retina Disease 2 94.60 High High
Cataract 1 91.88 High High
Ocular Toxicity (including Many Sub-types) 3 91.48 High High
Muscular Dystrophy 97 78.40 Quite High
Blister 1 71.92 Quite High
Necrosis 2 38.16 Quite Low
Targeted Disruption 1 36.32 Quite Low
Osteoporosis 36 30.48 Quite Low
Cytomegalovirus Infection 23 28.84 Quite Low
Paralysis 2 28.32 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For AP and dystrophin expression, mouse eyes were enucleated and snap frozen in liquid nitrogen–cooled isopentane in optimal cutting temperature (OCT) compound (Sakura Finetek Inc., Torrance, CA).
Regulation (enucleated) of Gene_expression (expression) of dystrophin in eyes
1) Confidence 0.44 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2713732 Disease Relevance 0.44 Pain Relevance 0.09
Dystrophin expression was evaluated in 40 muscle fibres selected at random on one representative transverse MANDYS 106-stained region per biopsy.
Regulation (evaluated) of Gene_expression (expression) of Dystrophin in muscle
2) Confidence 0.44 Published 2009 Journal Lancet Neurol Section Body Doc Link PMC2755039 Disease Relevance 0 Pain Relevance 0
So far there have been no developmental studies including the influences of innervation and contractile activity on the expression of dystrophin in cultured human muscle.
Regulation (influences) of Gene_expression (expression) of dystrophin in muscle
3) Confidence 0.26 Published 1991 Journal Brain Res. Section Abstract Doc Link 1668813 Disease Relevance 0.15 Pain Relevance 0.08
Post hoc analysis was performed to assess the effect of baseline glucocorticoid dose on BMD values at the lumbar spine, femoral neck, and total hip in patients treated with teriparatide or alendronate.37 For the analysis, patients were divided into a low-dose glucocorticoid group (?
Regulation (effect) of Gene_expression (values) of BMD in hip
4) Confidence 0.06 Published 2010 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2963159 Disease Relevance 0 Pain Relevance 0
Human dystrophin expression in muscles of GRDM dogs
Regulation (muscles) of Gene_expression (expression) of dystrophin in muscles
5) Confidence 0.03 Published 2008 Journal J Transl Med Section Body Doc Link PMC2529267 Disease Relevance 0 Pain Relevance 0

General Comments

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