INT134043

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Context Info
Confidence 0.31
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Title
Documents 1
Total Number 1
Disease Relevance 0.22
Pain Relevance 0.76

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Jak2, Akt1) cytosol (Jak2, Akt1) signal transduction (Jak2, Akt1)
nucleus (Jak2, Akt1) nucleoplasm (Akt1) cell differentiation (Jak2)
Jak2 (Rattus norvegicus)
Akt1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Opioid 4 99.46 Very High Very High Very High
ischemia 3 89.40 High High
Morphine 4 82.40 Quite High
MU agonist 1 80.96 Quite High
Disease Link Frequency Relevance Heat
Cv Unclassified Under Development 3 89.40 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The JAK/STAT pathway is essential for opioid-induced cardioprotection: JAK2 as a mediator of STAT3, Akt, and GSK-3 beta.
JAK2 Positive_regulation (mediator) of Akt associated with opioid
1) Confidence 0.31 Published 2006 Journal Am. J. Physiol. Heart Circ. Physiol. Section Title Doc Link 16517948 Disease Relevance 0.22 Pain Relevance 0.76

General Comments

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