INT134114

Context Info Confidence 0.00 First Reported 2006 Last Reported 2006 Negated 0 Speculated 0 Reported most in Title Documents 1 Total Number 1 Disease Relevance 0.47 Pain Relevance 0.41

plasma membrane (Gnai2, Oprd1, ADCY1) GTPase activity (Gnai2, ADCY1) cytoplasm (Gnai2, Oprd1) signal transducer activity (Gnai2, Oprd1) nucleus (Gnai2, ADCY1) small molecule metabolic process (ADCY1)

Gnai2 (Rattus norvegicus) Oprd1 (Rattus norvegicus) ADCY1 (Homo sapiens)

Pain Link Frequency Relevance Heat opioid receptor 8 100.00 narcan 2 99.58 Enkephalin 1 73.92 antagonist 1 52.48 agonist 1 40.88

Disease Link Frequency Relevance Heat Neuroblastoma 2 99.84 Bordatella Infection 6 88.72

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Short- and long-term regulation of adenylyl cyclase activity by delta-opioid receptor are mediated by Galphai2 in neuroblastoma N2A cells.

Galphai2 Positive_regulation (mediated) of opioid receptor Regulation (regulation) of adenylyl cyclase associated with neuroblastoma, narcan and opioid receptor

1) Confidence 0.00 Published 2006 Journal Mol. Pharmacol. Section Title Doc Link 16525132 Disease Relevance 0.47 Pain Relevance 0.41

General Comments

This test has worked.