INT134168

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.06
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.70
Pain Relevance 0.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (ADRA2B, APLP1) cell death (APLP1) cell adhesion (APLP1)
Golgi apparatus (APLP1) extracellular matrix organization (APLP1) cytoplasm (APLP1)
ADRA2B (Homo sapiens)
APLP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 8 84.24 Quite High
Analgesic 2 75.52 Quite High
Disease Link Frequency Relevance Heat
Disease 2 96.32 Very High Very High Very High
Alzheimer's Dementia 6 94.32 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
GST affinity chromatography revealed that APLP1 specifically interacts with all three human alpha2-adrenergic receptor subtypes and deletion mutant analysis confined the APLP1 domain involved in binding to alpha2-adrenergic receptors to the 13 amino acid residues Ser599-Ala611.
alpha2-adrenergic Binding (binding) of APLP1
1) Confidence 0.06 Published 2006 Journal Cell. Signal. Section Abstract Doc Link 16531006 Disease Relevance 0.34 Pain Relevance 0.18
GST affinity chromatography revealed that APLP1 specifically interacts with all three human alpha2-adrenergic receptor subtypes and deletion mutant analysis confined the APLP1 domain involved in binding to alpha2-adrenergic receptors to the 13 amino acid residues Ser599-Ala611.
alpha2-adrenergic Binding (interacts) of APLP1
2) Confidence 0.05 Published 2006 Journal Cell. Signal. Section Abstract Doc Link 16531006 Disease Relevance 0.36 Pain Relevance 0.19

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox