INT134255

Context Info Confidence 0.78 First Reported 2006 Last Reported 2006 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0.13

transport (Abcb1b) mitochondrion (Abcb1b) ATPase activity (Abcb1b) transmembrane transport (Abcb1b)

Anatomy Link Frequency lymphocyte 1 Abcb1b (Mus musculus)

Pain Link Frequency Relevance Heat antinociception 1 69.08 Opioid 1 62.04 Analgesic 2 25.00 Pain 1 25.00

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Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

These results indicate that the P-glycoprotein localized in the blood-brain barrier and, to a lesser extent, the testes-blood barrier is more resistant to inhibition than at other tissue sites such as the lymphocyte; moreover, the extent of this effect depends on the inhibitor.

Localization (localized) of P-glycoprotein in lymphocyte

1) Confidence 0.78 Published 2006 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 16537797 Disease Relevance 0 Pain Relevance 0.13

General Comments

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