INT134259

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Context Info
Confidence 0.11
First Reported 2006
Last Reported 2009
Negated 0
Speculated 1
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.93
Pain Relevance 0.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Ccl2) aging (Ccl2) extracellular region (Ccl2)
cytoskeleton organization (Ccl2) cytoplasm (Ccl2)
Anatomy Link Frequency
bowel 2
Ccl2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 25 99.88 Very High Very High Very High
cytokine 4 83.60 Quite High
Inflammatory mediators 3 75.00 Quite High
anesthesia 2 66.04 Quite High
isoflurane 1 65.60 Quite High
fibrosis 5 5.00 Very Low Very Low Very Low
chemokine 3 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 26 99.88 Very High Very High Very High
Sepsis 4 92.64 High High
Obesity 38 73.20 Quite High
Gastric Motility Disorder 1 62.04 Quite High
Injury 5 26.52 Quite Low
Nash(non-alcoholic Steatohepatitis) 12 5.00 Very Low Very Low Very Low
Fibrosis 5 5.00 Very Low Very Low Very Low
Adhesions 5 5.00 Very Low Very Low Very Low
Disease 5 5.00 Very Low Very Low Very Low
Liver Disease 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Inflammatory mRNA expressions for small bowel IL-6 and MCP-1 were significantly reduced after biliverdin treatment in CLP-induced septic animals compared with untreated septic animals.
Negative_regulation (reduced) of Transcription (expressions) of MCP-1 in bowel associated with inflammation
1) Confidence 0.11 Published 2006 Journal Am. J. Physiol. Gastrointest. Liver Physiol. Section Abstract Doc Link 16537973 Disease Relevance 0.75 Pain Relevance 0.37
Relative mRNA expression of ICAM-1, MCP-1, IL-6, and P-selectin was determined using predeveloped assays for real-time PCR (Applied Biosystems, Foster City, CA).
Spec (determined) Negative_regulation (determined) of Spec (determined) Transcription (expression) of MCP-1
2) Confidence 0.06 Published 2009 Journal Mediators of Inflammation Section Body Doc Link PMC2817554 Disease Relevance 0.18 Pain Relevance 0.06

General Comments

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