INT134339

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Context Info
Confidence 0.56
First Reported 2006
Last Reported 2010
Negated 0
Speculated 2
Reported most in Body
Documents 8
Total Number 10
Disease Relevance 3.19
Pain Relevance 0.54

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (CD55) plasma membrane (CD55)
Anatomy Link Frequency
epithelial cells 1
CD55 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 82 97.52 Very High Very High Very High
Etanercept 2 97.52 Very High Very High Very High
peptic ulcer disease 3 86.52 High High
Pain 4 50.00 Quite Low
Crohn's disease 14 5.00 Very Low Very Low Very Low
alcohol 11 5.00 Very Low Very Low Very Low
cytokine 9 5.00 Very Low Very Low Very Low
cva 4 5.00 Very Low Very Low Very Low
Nicotine 3 5.00 Very Low Very Low Very Low
eye pain 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 95 99.04 Very High Very High Very High
Apoptosis 11 99.04 Very High Very High Very High
INFLAMMATION 74 97.52 Very High Very High Very High
Death 4 97.16 Very High Very High Very High
Chronic Lymphoid Leukemia 94 96.72 Very High Very High Very High
Toxicity 13 93.92 High High
Adenocarcinoma 24 87.88 High High
Disease 84 86.52 High High
Ulcers 17 86.20 High High
Residual Neoplasm 6 84.28 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The VR method provides assessment of functional CROM and can be used for CROM enhancement.
Positive_regulation (enhancement) of CROM
1) Confidence 0.56 Published 2010 Journal Spine Section Body Doc Link 20110842 Disease Relevance 0 Pain Relevance 0
A single session exposure to VR resulted in a significant increase in CROM.
Positive_regulation (increase) of CROM
2) Confidence 0.56 Published 2010 Journal Spine Section Body Doc Link 20110842 Disease Relevance 0 Pain Relevance 0
Membrane-bound CRegs (Fig. 1) include decay-accelerating factor (DAF, CD55), membrane co-factor protein (MCP, CD46), complement receptor 1 (CR1, CD35), and membrane inhibitor of reactive lysis (MIRL, CD59).
Positive_regulation (include) of decay-accelerating factor
3) Confidence 0.27 Published 2008 Journal Semin Immunopathol Section Body Doc Link PMC2315691 Disease Relevance 0 Pain Relevance 0
Membrane-bound CRegs (Fig. 1) include decay-accelerating factor (DAF, CD55), membrane co-factor protein (MCP, CD46), complement receptor 1 (CR1, CD35), and membrane inhibitor of reactive lysis (MIRL, CD59).
Positive_regulation (include) of DAF
4) Confidence 0.27 Published 2008 Journal Semin Immunopathol Section Body Doc Link PMC2315691 Disease Relevance 0 Pain Relevance 0
In cultured gastric epithelial cells, H. pylori induced transcriptional up-regulation of DAF, and genetic deficiency of DAF attenuated the development of inflammation among H. pylori-infected mice.
Positive_regulation (up-regulation) of DAF in epithelial cells associated with inflammation
5) Confidence 0.19 Published 2006 Journal J. Biol. Chem. Section Abstract Doc Link 16543227 Disease Relevance 0.57 Pain Relevance 0.15
In this study, we investigated whether H. pylori utilizes DAF as a receptor and the role of DAF within H. pylori-infected gastric mucosa.
Spec (whether) Positive_regulation (utilizes) of DAF
6) Confidence 0.14 Published 2006 Journal J. Biol. Chem. Section Abstract Doc Link 16543227 Disease Relevance 0.63 Pain Relevance 0.15
In this study, we investigated whether H. pylori utilizes DAF as a receptor and the role of DAF within H. pylori-infected gastric mucosa.
Spec (whether) Positive_regulation (utilizes) of DAF
7) Confidence 0.12 Published 2006 Journal J. Biol. Chem. Section Abstract Doc Link 16543227 Disease Relevance 0.63 Pain Relevance 0.15
Membrane-bound CRegs (Fig. 1) include decay-accelerating factor (DAF, CD55), membrane co-factor protein (MCP, CD46), complement receptor 1 (CR1, CD35), and membrane inhibitor of reactive lysis (MIRL, CD59).
Positive_regulation (include) of CD55
8) Confidence 0.12 Published 2008 Journal Semin Immunopathol Section Body Doc Link PMC2315691 Disease Relevance 0 Pain Relevance 0
upregulates CD55 and CD59 antigens,60–64 a combination schedule that combines etanercept, a TNF-?
Positive_regulation (upregulates) of CD55 associated with etanercept
9) Confidence 0.11 Published 2010 Journal Cancer management and research Section Body Doc Link PMC3004569 Disease Relevance 1.02 Pain Relevance 0.09
Perhaps due to its ubiquitous expression, it is thought that bacterial pathogens, including uropathogenic Escherichia coli, use CD55 as a receptor prior to infection.
Positive_regulation (use) of CD55 associated with infection
10) Confidence 0.10 Published 2006 Journal J Transl Med Section Body Doc Link PMC1479838 Disease Relevance 0.34 Pain Relevance 0

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