INT134363

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Context Info
Confidence 0.00
First Reported 2006
Last Reported 2006
Negated 0
Speculated 1
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.14
Pain Relevance 1.70

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Prkcg, ADCY2) plasma membrane (Prkcg, ADCY2) small molecule metabolic process (ADCY2)
intracellular (Prkcg) GTPase activity (ADCY2) protein complex (ADCY2)
Prkcg (Rattus norvegicus)
ADCY2 (Homo sapiens)
Pain Link Frequency Relevance Heat
MU agonist 2 97.96 Very High Very High Very High
Opioid 16 94.80 High High
Morphine 2 84.04 Quite High
agonist 2 83.36 Quite High
opioid receptor 2 76.80 Quite High
narcan 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Bordatella Infection 2 72.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We investigated the regulation of AC-II by Galphas and by PKC under conditions of acute and chronic exposure to opioid agonists in COS-7 transfected cells.
PKC Spec (investigated) Regulation (regulation) of AC-II associated with mu agonist
1) Confidence 0.00 Published 2006 Journal Neuropharmacology Section Abstract Doc Link 16545401 Disease Relevance 0.07 Pain Relevance 0.87
AC-II is highly regulated by multiple and independent biochemical stimuli, including Gbetagamma, Galphas and PKC activation.
PKC Regulation (regulated) of AC-II
2) Confidence 0.00 Published 2006 Journal Neuropharmacology Section Abstract Doc Link 16545401 Disease Relevance 0.07 Pain Relevance 0.83

General Comments

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