INT134513

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Context Info
Confidence 0.37
First Reported 2006
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Slc12a3) transport (Slc12a3) plasma membrane (Slc12a3)
transmembrane transport (Slc12a3)
Anatomy Link Frequency
ascending limb 1
Slc12a3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
anesthesia 2 86.24 High High
Disease Link Frequency Relevance Heat
Acute Renal Failure 3 5.00 Very Low Very Low Very Low
Sepsis 2 5.00 Very Low Very Low Very Low
Natriuresis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The HS diet also caused a redistribution of NCC from low to higher density membranes.
Negative_regulation (redistribution) of NCC
1) Confidence 0.37 Published 2006 Journal Am. J. Physiol. Renal Physiol. Section Abstract Doc Link 16554416 Disease Relevance 0 Pain Relevance 0.09
Thick ascending limb sodium transporters NHE3 and NKCC2 were downregulated in ISOM and NaPi2 was decreased in CTX/OSOM, whereas NCC and ENaC were not consistently downregulated.
Neg (not) Negative_regulation (downregulated) of NCC in ascending limb
2) Confidence 0.18 Published 2009 Journal Nephrol. Dial. Transplant. Section Body Doc Link 19193739 Disease Relevance 0 Pain Relevance 0

General Comments

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