INT134733

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Context Info
Confidence 0.66
First Reported 2002
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 6
Total Number 6
Disease Relevance 0.56
Pain Relevance 1.61

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Dab1) cytosol (Dab1) intracellular (Dab1)
Anatomy Link Frequency
dorsal horn 4
brain 1
Dab1 (Mus musculus)
Pain Link Frequency Relevance Heat
Pain 13 97.88 Very High Very High Very High
Dorsal horn 12 97.00 Very High Very High Very High
Spinal cord 15 93.48 High High
Neuropeptide 2 76.16 Quite High
GABA receptor 1 75.08 Quite High
anesthesia 1 74.96 Quite High
Somatostatin 3 73.60 Quite High
Serotonin 1 71.56 Quite High
gABA 2 70.20 Quite High
Glutamate receptor 1 69.00 Quite High
Disease Link Frequency Relevance Heat
Adhesions 1 90.80 High High
Neurodegenerative Disease 6 87.08 High High
Nociception 9 82.44 Quite High
Targeted Disruption 18 45.68 Quite Low
Congenital Anomalies 4 39.92 Quite Low
Hyperalgesia 4 30.16 Quite Low
Pain 9 27.60 Quite Low
Ganglion Cysts 70 23.52 Low Low
Repression 4 5.00 Very Low Very Low Very Low
Hypersensitivity 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We used immunocytochemistry to map the distribution of Reelin and Disabled-1 (the protein product of the reeler gene, and the intracellular adaptor protein, Dab1, involved in its signaling pathway) in adjacent regions of the developing dorsal horn, from early to late embryonic development.
Gene_expression (product) of Disabled-1 in dorsal horn associated with dorsal horn
1) Confidence 0.66 Published 2006 Journal Neuroscience Section Abstract Doc Link 16580148 Disease Relevance 0.07 Pain Relevance 0.30
We used immunocytochemistry to map the distribution of Reelin and Disabled-1 (the protein product of the reeler gene, and the intracellular adaptor protein, Dab1, involved in its signaling pathway) in adjacent regions of the developing dorsal horn, from early to late embryonic development.
Gene_expression (product) of Dab1 in dorsal horn associated with dorsal horn
2) Confidence 0.66 Published 2006 Journal Neuroscience Section Abstract Doc Link 16580148 Disease Relevance 0.07 Pain Relevance 0.33
We used immunocytochemistry to map the distribution of Reelin and Disabled-1 (the protein product of the reeler gene, and the intracellular adaptor protein, Dab1, involved in its signaling pathway) in adjacent regions of the developing dorsal horn, from early to late embryonic development.
Gene_expression (distribution) of Dab1 in dorsal horn associated with dorsal horn
3) Confidence 0.66 Published 2006 Journal Neuroscience Section Abstract Doc Link 16580148 Disease Relevance 0.07 Pain Relevance 0.34
We used immunocytochemistry to map the distribution of Reelin and Disabled-1 (the protein product of the reeler gene, and the intracellular adaptor protein, Dab1, involved in its signaling pathway) in adjacent regions of the developing dorsal horn, from early to late embryonic development.
Gene_expression (distribution) of Disabled-1 in dorsal horn associated with dorsal horn
4) Confidence 0.66 Published 2006 Journal Neuroscience Section Abstract Doc Link 16580148 Disease Relevance 0.07 Pain Relevance 0.31
This is illustrated by the cloning of Nam16, a novel gene differentially expressed in the brain of normal and Dab1-deficient mice.


Gene_expression (expressed) of Dab1 in brain
5) Confidence 0.61 Published 2002 Journal BMC Mol Biol Section Body Doc Link PMC113762 Disease Relevance 0 Pain Relevance 0.07
Increased expression was also noted for several molecules with known or likely roles in axon guidance, including Disabled1, Sema3c, Sema3d, f-spondin, Cadherin22, Protocadherin 8, Protocadherin 17, Dcc, and NetrinG1.
Gene_expression (expression) of Disabled1
6) Confidence 0.00 Published 2007 Journal Neural Develop Section Body Doc Link PMC1796875 Disease Relevance 0.26 Pain Relevance 0.25

General Comments

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