INT134741

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Context Info
Confidence 0.23
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.70
Pain Relevance 1.69

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (NMT2) Golgi apparatus (NMT2) plasma membrane (NMT2)
transferase activity, transferring acyl groups (NMT2) cytoplasm (NMT2)
NMT2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Analgesic 8 100.00 Very High Very High Very High
Pain 8 100.00 Very High Very High Very High
Calcium channel 8 100.00 Very High Very High Very High
Lasting pain 2 97.48 Very High Very High Very High
Neuronal excitability 2 90.68 High High
Disease Link Frequency Relevance Heat
Pain 6 98.00 Very High Very High Very High
Nociception 4 93.52 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Targeting N-type and T-type calcium channels for the treatment of pain.
Regulation (Targeting) of N-type associated with pain, analgesic and calcium channel
1) Confidence 0.23 Published 2006 Journal Drug Discov. Today Section Title Doc Link 16580601 Disease Relevance 0.37 Pain Relevance 1.05
Although multiple subtypes of voltage-gated calcium channels exist, pharmacological and ion-channel gene knockdown approaches in animals have revealed N-type and T-type calcium channels to be particularly attractive molecular targets for the discovery and development of new analgesic drugs.
Regulation (targets) of N-type associated with analgesic and calcium channel
2) Confidence 0.23 Published 2006 Journal Drug Discov. Today Section Abstract Doc Link 16580601 Disease Relevance 0.33 Pain Relevance 0.64

General Comments

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