INT134823

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Context Info
Confidence 0.27
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.38
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (Bcar1) plasma membrane (Bcar1) cytoplasm (Bcar1)
Bcar1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
agonist 20 90.64 High High
Analgesic 1 84.24 Quite High
Glutamate 6 5.00 Very Low Very Low Very Low
Action potential 3 5.00 Very Low Very Low Very Low
tetrodotoxin 2 5.00 Very Low Very Low Very Low
depression 2 5.00 Very Low Very Low Very Low
Glutamate receptor 2 5.00 Very Low Very Low Very Low
Neurotransmitter 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Chromosome Aberrations 4 100.00 Very High Very High Very High
Depression 2 5.00 Very Low Very Low Very Low
Recurrence 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This range of CaS has been previously been reported in in vitro preparations (Womack and Khodakhah, 2004; McKay et al., 2005; Achard and De Schutter, 2008), however this is the first time it has been shown how easily the CaS can be activated by kainate receptors (100% activation of CaS).
Positive_regulation (activated) of Positive_regulation (activation) of CaS
1) Confidence 0.27 Published 2010 Journal Frontiers in Neural Circuits Section Body Doc Link PMC2876879 Disease Relevance 0 Pain Relevance 0.09
S9 increased the induction of CAs in a dose-dependent manner to 15% at 2500 microM, with a high frequency of chromatid exchanges.
Positive_regulation (increased) of Positive_regulation (induction) of CAs associated with chromosome aberrations
2) Confidence 0.21 Published 2006 Journal Mutagenesis Section Abstract Doc Link 16595588 Disease Relevance 0.38 Pain Relevance 0.08

General Comments

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