INT134856

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Context Info
Confidence 0.48
First Reported 2006
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.30
Pain Relevance 0.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (FGF10) extracellular region (FGF10) plasma membrane (FGF10)
nucleus (FGF10) cell-cell signaling (FGF10)
Anatomy Link Frequency
urothelial cell 1
patterning 1
FGF10 (Homo sapiens)
Pain Link Frequency Relevance Heat
midbrain 20 99.32 Very High Very High Very High
Dopamine 83 95.16 Very High Very High Very High
chemokine 2 84.24 Quite High
interstitial cystitis 1 66.24 Quite High
Action potential 4 5.00 Very Low Very Low Very Low
gABA 3 5.00 Very Low Very Low Very Low
Glutamate 3 5.00 Very Low Very Low Very Low
tetrodotoxin 1 5.00 Very Low Very Low Very Low
drug abuse 1 5.00 Very Low Very Low Very Low
Neurotransmitter 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neurodegenerative Disease 7 95.04 Very High Very High Very High
Nervous System Malformation 1 72.60 Quite High
Injury 1 69.44 Quite High
Urinary Tract Disease 1 63.84 Quite High
Disease 3 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low
Parkinson's Disease 1 5.00 Very Low Very Low Very Low
Mucocutaneous Lymph Node Syndrome 1 5.00 Very Low Very Low Very Low
Cancer 1 5.00 Very Low Very Low Very Low
Interstitial Cystitis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Deconvolution, light and transmission electron microscopic studies captured FGF-10 and its receptor in association with the urothelial cell surface, in cytoplasm, and within nuclei, observations that describe the mechanism that transduces the mitogenic signal in these tissues.
FGF-10 Binding (association) of in urothelial cell
1) Confidence 0.48 Published 2006 Journal Am. J. Physiol. Renal Physiol. Section Abstract Doc Link 16597614 Disease Relevance 0.13 Pain Relevance 0.07
These interactions of FGF10 with well-known midbrain patterning cues suggests that this factor may be involved in FGF8 and SHH signaling to enhance DA neurogenesis.
FGF10 Binding (interactions) of in patterning associated with dopamine, midbrain and neurodegenerative disease
2) Confidence 0.27 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2719871 Disease Relevance 0.17 Pain Relevance 0.36

General Comments

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