INT134871

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Context Info
Confidence 0.00
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.41
Pain Relevance 1.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell cycle (Calm3)
Calm3 (Mus musculus)
IQCJ (Homo sapiens)
Pain Link Frequency Relevance Heat
nav1.8 12 98.58 Very High Very High Very High
dorsal root ganglion 6 87.04 High High
sodium channel 3 75.00 Quite High
Action potential 1 74.44 Quite High
tetrodotoxin 1 66.20 Quite High
Disease Link Frequency Relevance Heat
Ganglion Cysts 6 87.04 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To investigate the functional role of CaM binding to the IQ motif in the Nav1.8 C-terminus, the IQ dipeptide was substituted by DE; we show that this impairs the binding of CaM to the IQ motif.
Negative_regulation (impairs) of CaM Binding (binding) of IQ motif associated with nav1.8
1) Confidence 0.00 Published 2006 Journal J. Neurophysiol. Section Abstract Doc Link 16598065 Disease Relevance 0.41 Pain Relevance 1.17

General Comments

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