INT134879

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Context Info
Confidence 0.50
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.27
Pain Relevance 0.93

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Nos1) aging (Nos1) enzyme binding (Nos1)
cytoplasm (Nos1) cytosol (Nos1) oxidoreductase activity (Nos1)
Nos1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Morphine 11 99.98 Very High Very High Very High
depression 3 98.96 Very High Very High Very High
Dextromethorphan 3 92.04 High High
Hippocampus 1 75.00 Quite High
Neuronal nitric oxide synthase 1 59.00 Quite High
Central nervous system 1 45.44 Quite Low
withdrawal 1 42.20 Quite Low
Disease Link Frequency Relevance Heat
Depression 3 98.96 Very High Very High Very High
Opiate Addiction 1 42.56 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Collectively, the study demonstrates that maternal exposure to morphine decreases the magnitude of PSD-95, nNOS, the phosphorylation of CREB(Serine-133), and LTD expression in hippocampal CA1 subregion of young offspring (e.g., P14).
Negative_regulation (decreases) of Phosphorylation (phosphorylation) of nNOS associated with depression and morphine
1) Confidence 0.50 Published 2006 Journal Hippocampus Section Abstract Doc Link 16598705 Disease Relevance 0.27 Pain Relevance 0.93

General Comments

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