INT134923

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Context Info
Confidence 0.70
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 5
Total Number 5
Disease Relevance 3.87
Pain Relevance 0.70

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Enox2) oxidoreductase activity (Enox2) extracellular region (Enox2)
plasma membrane (Enox2)
Anatomy Link Frequency
lung 2
Enox2 (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 56 97.20 Very High Very High Very High
qutenza 8 94.96 High High
positron emission tomography 39 89.76 High High
Inflammation 1 43.44 Quite Low
anesthesia 10 5.00 Very Low Very Low Very Low
ketamine 6 5.00 Very Low Very Low Very Low
isoflurane 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 100 100.00 Very High Very High Very High
Targeted Disruption 8 99.88 Very High Very High Very High
Adenocarcinoma 5 99.64 Very High Very High Very High
Apoptosis 4 74.52 Quite High
Colon Cancer 16 73.44 Quite High
Disease 4 60.60 Quite High
INFLAMMATION 1 43.44 Quite Low
Metastasis 1 37.28 Quite Low
Body Weight 1 5.00 Very Low Very Low Very Low
Lewis Lung Carcinoma 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Transgenic mice grew faster and the increased growth caused by tNOX overexpression was blocked by EGCg in the drinking water.
Positive_regulation (overexpression) of Gene_expression (overexpression) of tNOX associated with targeted disruption
1) Confidence 0.70 Published 2006 Journal Rejuvenation Res Section Abstract Doc Link 16608395 Disease Relevance 0.72 Pain Relevance 0.08
Vector-forced overexpression of tNOX cDNA and antisense has demonstrated that the tNOX target is both necessary and sufficient to explain the anticancer properties of green tea catechins alone and in vanilloid-containing combinations.
Positive_regulation (overexpression) of Gene_expression (overexpression) of tNOX
2) Confidence 0.70 Published 2006 Journal Rejuvenation Res Section Abstract Doc Link 16608395 Disease Relevance 0.75 Pain Relevance 0.09
Vector-forced overexpression of tNOX cDNA and antisense has demonstrated that the tNOX target is both necessary and sufficient to explain the anticancer properties of green tea catechins alone and in vanilloid-containing combinations.
Positive_regulation (necessary) of Gene_expression (overexpression) of tNOX
3) Confidence 0.47 Published 2006 Journal Rejuvenation Res Section Abstract Doc Link 16608395 Disease Relevance 0.76 Pain Relevance 0.09
The necessity and sufficiency of tNOX was validated as the catechin target with transgenic mice overexpressing the processed form of tNOX.
Positive_regulation (overexpressing) of Gene_expression (overexpressing) of tNOX associated with targeted disruption
4) Confidence 0.44 Published 2006 Journal Rejuvenation Res Section Abstract Doc Link 16608395 Disease Relevance 0.75 Pain Relevance 0.08
In that regard, tumor-associated glycoprotein-72 (TAG-72) is a mucin-like glycoprotein complex that is overexpressed by many adenocarcinomas, including colorectal, pancreatic, gastric, esophageal, ovarian, endometrial, breast, prostate, and lung [22,24-27].
Positive_regulation (overexpressed) of Gene_expression (overexpressed) of tumor-associated glycoprotein-72 in lung associated with adenocarcinoma and cancer
5) Confidence 0.05 Published 2010 Journal World J Surg Oncol Section Body Doc Link PMC2924340 Disease Relevance 0.89 Pain Relevance 0.34

General Comments

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